LOC114841037 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf82	C9orf135	ENSP00000465712	ENSP00000366402	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Protein C9orf135; Chromosome 9 open reading frame 135.	0.914
C10orf82	CCDC105	ENSP00000465712	ENSP00000292574	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Coiled-coil domain containing 105.	0.916
C10orf82	CFAP161	ENSP00000465712	ENSP00000286732	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.	0.869
C10orf82	CFAP20	ENSP00000465712	ENSP00000262498	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	0.817
C10orf82	EFCAB6	ENSP00000465712	ENSP00000262726	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.883
C10orf82	LOC114841037	ENSP00000465712	ENSP00000362054	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Guanylyl cyclase-activating protein 1.	0.838
C10orf82	SPAG8	ENSP00000465712	ENSP00000340982	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis. May play a role in fertility and microtubule formation through interaction with RANBP9.	0.883
C10orf82	TEKT2	ENSP00000465712	ENSP00000207457	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.901
C10orf82	TEKT5	ENSP00000465712	ENSP00000283025	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Tektin-5; May be a structural component of the sperm flagellum.	0.871
C10orf82	TEPP	ENSP00000465712	ENSP00000290871	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Testis, prostate and placenta expressed.	0.839
C9orf135	C10orf82	ENSP00000366402	ENSP00000465712	Protein C9orf135; Chromosome 9 open reading frame 135.	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	0.914
C9orf135	CCDC105	ENSP00000366402	ENSP00000292574	Protein C9orf135; Chromosome 9 open reading frame 135.	Coiled-coil domain containing 105.	0.926
C9orf135	CFAP161	ENSP00000366402	ENSP00000286732	Protein C9orf135; Chromosome 9 open reading frame 135.	Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.	0.893
C9orf135	CFAP20	ENSP00000366402	ENSP00000262498	Protein C9orf135; Chromosome 9 open reading frame 135.	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	0.957
C9orf135	EFCAB6	ENSP00000366402	ENSP00000262726	Protein C9orf135; Chromosome 9 open reading frame 135.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.906
C9orf135	LOC114841037	ENSP00000366402	ENSP00000362054	Protein C9orf135; Chromosome 9 open reading frame 135.	Guanylyl cyclase-activating protein 1.	0.839
C9orf135	SPAG8	ENSP00000366402	ENSP00000340982	Protein C9orf135; Chromosome 9 open reading frame 135.	Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis. May play a role in fertility and microtubule formation through interaction with RANBP9.	0.937
C9orf135	TEKT2	ENSP00000366402	ENSP00000207457	Protein C9orf135; Chromosome 9 open reading frame 135.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.969
C9orf135	TEKT5	ENSP00000366402	ENSP00000283025	Protein C9orf135; Chromosome 9 open reading frame 135.	Tektin-5; May be a structural component of the sperm flagellum.	0.904
C9orf135	TEPP	ENSP00000366402	ENSP00000290871	Protein C9orf135; Chromosome 9 open reading frame 135.	Testis, prostate and placenta expressed.	0.897