S100PBP protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	S100PBP	ENSP00000220592	ENSP00000362574	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	S100P binding protein.	0.471
FAM89A	S100PBP	ENSP00000355614	ENSP00000362574	Protein FAM89A; Family with sequence similarity 89 member A; Belongs to the FAM89 family.	S100P binding protein.	0.487
PCED1B	S100PBP	ENSP00000446688	ENSP00000362574	PC-esterase domain containing 1B; Belongs to the PC-esterase family.	S100P binding protein.	0.849
S100P	S100PBP	ENSP00000296370	ENSP00000362574	Protein S100-P; May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE); Belongs to the S-100 family.	S100P binding protein.	0.964
S100PBP	AGO2	ENSP00000362574	ENSP00000220592	S100P binding protein.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.471
S100PBP	FAM89A	ENSP00000362574	ENSP00000355614	S100P binding protein.	Protein FAM89A; Family with sequence similarity 89 member A; Belongs to the FAM89 family.	0.487
S100PBP	PCED1B	ENSP00000362574	ENSP00000446688	S100P binding protein.	PC-esterase domain containing 1B; Belongs to the PC-esterase family.	0.849
S100PBP	S100P	ENSP00000362574	ENSP00000296370	S100P binding protein.	Protein S100-P; May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE); Belongs to the S-100 family.	0.964
S100PBP	ZG16B	ENSP00000362574	ENSP00000371715	S100P binding protein.	Zymogen granule protein 16B; Belongs to the jacalin lectin family.	0.565
ZG16B	S100PBP	ENSP00000371715	ENSP00000362574	Zymogen granule protein 16B; Belongs to the jacalin lectin family.	S100P binding protein.	0.565