STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLPSL1Colipase-like protein 1; Colipase like 1; Belongs to the colipase family. (121 aa)    
Predicted Functional Partners:
NUDT15
Nucleotide triphosphate diphosphatase NUDT15; May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP. Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives. Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides t [...]
    
   0.591
C3orf22
Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.
      
 0.578
C4orf51
Uncharacterized protein C4orf51; Chromosome 4 open reading frame 51.
      
 0.578
RNASE12
Probable inactive ribonuclease-like protein 12; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
      
 0.570
SMIM17
Small integral membrane protein 17.
      
 0.515
C12orf56
Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.
      
 0.512
KRTAP4-6
Keratin associated protein 4-6.
      
 0.507
SH2D7
SH2 domain containing 7.
      
 0.480
C22orf42
Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.
      
 0.479
CC2D2B
Protein CC2D2B; Coiled-coil and C2 domain containing 2B.
      
 0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.