node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRINP2 | PHYHIPL | ENSP00000354481 | ENSP00000362987 | BMP/retinoic acid-inducible neural-specific protein 2; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.409 |
PDE9A | PHYHIPL | ENSP00000291539 | ENSP00000362987 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its abi [...] | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.730 |
PHACTR3 | PHYHIPL | ENSP00000360054 | ENSP00000362987 | Phosphatase and actin regulator 3. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.522 |
PHACTR3 | TMA16 | ENSP00000360054 | ENSP00000351380 | Phosphatase and actin regulator 3. | Translation machinery associated 16 homolog. | 0.528 |
PHYHIPL | BRINP2 | ENSP00000362987 | ENSP00000354481 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | BMP/retinoic acid-inducible neural-specific protein 2; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. | 0.409 |
PHYHIPL | PDE9A | ENSP00000362987 | ENSP00000291539 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its abi [...] | 0.730 |
PHYHIPL | PHACTR3 | ENSP00000362987 | ENSP00000360054 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Phosphatase and actin regulator 3. | 0.522 |
PHYHIPL | PMPCB | ENSP00000362987 | ENSP00000249269 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. | 0.404 |
PHYHIPL | PSD2 | ENSP00000362987 | ENSP00000274710 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Pleckstrin and Sec7 domain containing 2. | 0.405 |
PHYHIPL | RASGEF1C | ENSP00000362987 | ENSP00000377037 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF). | 0.407 |
PHYHIPL | STARD7 | ENSP00000362987 | ENSP00000338030 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | StAR-related lipid transfer protein 7, mitochondrial; May play a protective role in mucosal tissues by preventing exaggerated allergic responses. | 0.410 |
PHYHIPL | TMA16 | ENSP00000362987 | ENSP00000351380 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Translation machinery associated 16 homolog. | 0.585 |
PHYHIPL | TMCO6 | ENSP00000362987 | ENSP00000252100 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Transmembrane and coiled-coil domains 6. | 0.609 |
PHYHIPL | TMEM143 | ENSP00000362987 | ENSP00000293261 | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | Transmembrane protein 143. | 0.446 |
PMPCB | PHYHIPL | ENSP00000249269 | ENSP00000362987 | Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.404 |
PSD2 | PHYHIPL | ENSP00000274710 | ENSP00000362987 | Pleckstrin and Sec7 domain containing 2. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.405 |
RASGEF1C | PHYHIPL | ENSP00000377037 | ENSP00000362987 | Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF). | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.407 |
STARD7 | PHYHIPL | ENSP00000338030 | ENSP00000362987 | StAR-related lipid transfer protein 7, mitochondrial; May play a protective role in mucosal tissues by preventing exaggerated allergic responses. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.410 |
TMA16 | PHACTR3 | ENSP00000351380 | ENSP00000360054 | Translation machinery associated 16 homolog. | Phosphatase and actin regulator 3. | 0.528 |
TMA16 | PHYHIPL | ENSP00000351380 | ENSP00000362987 | Translation machinery associated 16 homolog. | Phytanoyl-CoA hydroxylase-interacting protein-like; May play a role in the development of the central system. | 0.585 |