STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGAP5Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5; Putative GTPase-activating protein; Belongs to the centaurin gamma-like family. (686 aa)    
Predicted Functional Partners:
AGAP4
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Belongs to the centaurin gamma-like family.
  
   
0.538
AGAP6
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6; Putative GTPase-activating protein; Belongs to the centaurin gamma-like family.
  
   
0.531
FAM241A
Uncharacterized protein FAM241A; Family with sequence similarity 241 member A.
      
 0.521
HDHD3
Haloacid dehalogenase like hydrolase domain containing 3.
      
 0.475
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9.
  
   
0.445
MYOZ1
Myozenin-1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
      
 0.418
ZPLD1
Zona pellucida-like domain-containing protein 1, secreted form; Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
      
 0.416
TLL2
Tolloid-like protein 2; Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
      
 0.400
LMO3
LIM domain only 3.
      
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.