C10orf53 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf53	CFAP43	ENSP00000363226	ENSP00000349568	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.654
C10orf53	CFAP44	ENSP00000363226	ENSP00000377428	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.654
C10orf53	DNAH1	ENSP00000363226	ENSP00000401514	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family.	0.645
C10orf53	DNAH6	ENSP00000363226	ENSP00000374045	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Dynein heavy chain 6, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity); Belongs to the dynein heavy chain family.	0.654
C10orf53	DNALI1	ENSP00000363226	ENSP00000296218	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility.	0.685
C10orf53	LRRC23	ENSP00000363226	ENSP00000390932	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23.	0.660
C10orf53	MDH1B	ENSP00000363226	ENSP00000363533	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Malate dehydrogenase 1B.	0.654
C10orf53	MORN5	ENSP00000363226	ENSP00000362869	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	MORN repeat containing 5.	0.643
C10orf53	STYXL1	ENSP00000363226	ENSP00000248600	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.641
C10orf53	TTC29	ENSP00000363226	ENSP00000423505	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Tetratricopeptide repeat domain 29.	0.659
CFAP43	C10orf53	ENSP00000349568	ENSP00000363226	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	0.654
CFAP43	CFAP44	ENSP00000349568	ENSP00000377428	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.991
CFAP43	DNAH1	ENSP00000349568	ENSP00000401514	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family.	0.993
CFAP43	DNAH6	ENSP00000349568	ENSP00000374045	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Dynein heavy chain 6, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity); Belongs to the dynein heavy chain family.	0.988
CFAP43	DNALI1	ENSP00000349568	ENSP00000296218	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility.	0.938
CFAP43	LRRC23	ENSP00000349568	ENSP00000390932	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23.	0.758
CFAP43	MDH1B	ENSP00000349568	ENSP00000363533	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Malate dehydrogenase 1B.	0.851
CFAP43	MORN5	ENSP00000349568	ENSP00000362869	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	MORN repeat containing 5.	0.866
CFAP43	STYXL1	ENSP00000349568	ENSP00000248600	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.862
CFAP43	TTC29	ENSP00000349568	ENSP00000423505	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Tetratricopeptide repeat domain 29.	0.975