MDH1B protein (human) - STRING interaction network

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Score

MDH1B

Malate dehydrogenase 1B. (518 aa)

Predicted Functional Partners:

MORN5

0.874

GOT2

0.872

CFAP43

0.851

ZMYND12

0.849

AKAP14

0.847

DNAH6

0.842

TTC29

0.842

DNALI1

0.835

AK7

0.830

STYXL1

0.826

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK7	AKAP14	ENSP00000267584	ENSP00000360485	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	0.869
AK7	CFAP43	ENSP00000267584	ENSP00000349568	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.945
AK7	DNAH6	ENSP00000267584	ENSP00000374045	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Dynein heavy chain 6, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity); Belongs to the dynein heavy chain family.	0.946
AK7	DNALI1	ENSP00000267584	ENSP00000296218	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility.	0.955
AK7	MDH1B	ENSP00000267584	ENSP00000363533	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Malate dehydrogenase 1B.	0.830
AK7	MORN5	ENSP00000267584	ENSP00000362869	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	MORN repeat containing 5.	0.848
AK7	STYXL1	ENSP00000267584	ENSP00000248600	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.845
AK7	TTC29	ENSP00000267584	ENSP00000423505	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Tetratricopeptide repeat domain 29.	0.934
AK7	ZMYND12	ENSP00000267584	ENSP00000361646	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	Zinc finger MYND-type containing 12.	0.817
AKAP14	AK7	ENSP00000360485	ENSP00000267584	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	0.869
AKAP14	CFAP43	ENSP00000360485	ENSP00000349568	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.866
AKAP14	DNAH6	ENSP00000360485	ENSP00000374045	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Dynein heavy chain 6, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity); Belongs to the dynein heavy chain family.	0.817
AKAP14	DNALI1	ENSP00000360485	ENSP00000296218	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility.	0.835
AKAP14	MDH1B	ENSP00000360485	ENSP00000363533	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Malate dehydrogenase 1B.	0.847
AKAP14	MORN5	ENSP00000360485	ENSP00000362869	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	MORN repeat containing 5.	0.905
AKAP14	STYXL1	ENSP00000360485	ENSP00000248600	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.817
AKAP14	TTC29	ENSP00000360485	ENSP00000423505	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Tetratricopeptide repeat domain 29.	0.963
AKAP14	ZMYND12	ENSP00000360485	ENSP00000361646	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	Zinc finger MYND-type containing 12.	0.817
CFAP43	AK7	ENSP00000349568	ENSP00000267584	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.	0.945
CFAP43	AKAP14	ENSP00000349568	ENSP00000360485	Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function.	A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.	0.866