| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTL7B | CAPZA3 | ENSP00000363799 | ENSP00000326238 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.429 |
| ACTL7B | CTNNAL1 | ENSP00000363799 | ENSP00000320434 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). | 0.928 |
| ACTL7B | ENSP00000491073 | ENSP00000363799 | ENSP00000491073 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Uncharacterized protein. | 0.511 |
| ACTL7B | KLHL10 | ENSP00000363799 | ENSP00000293303 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.441 |
| ACTL7B | ODF1 | ENSP00000363799 | ENSP00000285402 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.476 |
| ACTL7B | TEKT4 | ENSP00000363799 | ENSP00000295201 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.419 |
| ACTL7B | TEKT5 | ENSP00000363799 | ENSP00000283025 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Tektin-5; May be a structural component of the sperm flagellum. | 0.401 |
| ACTL7B | TEX38 | ENSP00000363799 | ENSP00000455854 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Testis-expressed protein 38; Testis expressed 38. | 0.459 |
| ACTL7B | TRIM36 | ENSP00000363799 | ENSP00000282369 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | E3 ubiquitin-protein ligase TRIM36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization. Belongs to the TRIM/RBCC family. | 0.400 |
| ACTL7B | TSSK2 | ENSP00000363799 | ENSP00000382544 | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | Testis-specific serine/threonine-protein kinase 2; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. | 0.450 |
| CAPZA3 | ACTL7B | ENSP00000326238 | ENSP00000363799 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | 0.429 |
| CAPZA3 | KLHL10 | ENSP00000326238 | ENSP00000293303 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.439 |
| CAPZA3 | ODF1 | ENSP00000326238 | ENSP00000285402 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.527 |
| CAPZA3 | TEKT5 | ENSP00000326238 | ENSP00000283025 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Tektin-5; May be a structural component of the sperm flagellum. | 0.591 |
| CAPZA3 | TSSK2 | ENSP00000326238 | ENSP00000382544 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Testis-specific serine/threonine-protein kinase 2; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. | 0.566 |
| CTNNAL1 | ACTL7B | ENSP00000320434 | ENSP00000363799 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | 0.928 |
| ENSP00000491073 | ACTL7B | ENSP00000491073 | ENSP00000363799 | Uncharacterized protein. | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | 0.511 |
| KLHL10 | ACTL7B | ENSP00000293303 | ENSP00000363799 | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | Actin-like protein 7B; Actin like 7B; Belongs to the actin family. | 0.441 |
| KLHL10 | CAPZA3 | ENSP00000293303 | ENSP00000326238 | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.439 |
| KLHL10 | ODF1 | ENSP00000293303 | ENSP00000285402 | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.432 |
