VWA7 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VWA7

Von Willebrand factor A domain containing 7. (891 aa)

Predicted Functional Partners:

VARS1

0.969

VOPP1

0.613

LY6G6C

0.576

SAPCD1

0.570

E7ENX8_HUMAN

0.541

DPY19L4

0.528

TMEM9B

0.497

LY6G5C

0.492

CCNQ

0.491

NOC4L

0.490

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNQ	DPY19L4	ENSP00000402949	ENSP00000389630	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	0.535
CCNQ	NOC4L	ENSP00000402949	ENSP00000328854	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	0.507
CCNQ	TMEM9B	ENSP00000402949	ENSP00000433361	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family.	0.548
CCNQ	VWA7	ENSP00000402949	ENSP00000364840	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	Von Willebrand factor A domain containing 7.	0.491
DPY19L4	CCNQ	ENSP00000389630	ENSP00000402949	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	0.535
DPY19L4	NOC4L	ENSP00000389630	ENSP00000328854	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	0.531
DPY19L4	TMEM9B	ENSP00000389630	ENSP00000433361	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family.	0.543
DPY19L4	VWA7	ENSP00000389630	ENSP00000364840	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	Von Willebrand factor A domain containing 7.	0.528
E7ENX8_HUMAN	VWA7	ENSP00000391806	ENSP00000364840	Uncharacterized protein.	Von Willebrand factor A domain containing 7.	0.541
LY6G5C	LY6G6C	ENSP00000372724	ENSP00000364978	Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.	Lymphocyte antigen 6 family member G6C.	0.796
LY6G5C	VWA7	ENSP00000372724	ENSP00000364840	Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.	Von Willebrand factor A domain containing 7.	0.492
LY6G6C	LY6G5C	ENSP00000364978	ENSP00000372724	Lymphocyte antigen 6 family member G6C.	Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation.	0.796
LY6G6C	VWA7	ENSP00000364978	ENSP00000364840	Lymphocyte antigen 6 family member G6C.	Von Willebrand factor A domain containing 7.	0.576
NOC4L	CCNQ	ENSP00000328854	ENSP00000402949	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	0.507
NOC4L	DPY19L4	ENSP00000328854	ENSP00000389630	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	0.531
NOC4L	TMEM9B	ENSP00000328854	ENSP00000433361	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family.	0.500
NOC4L	VWA7	ENSP00000328854	ENSP00000364840	Nucleolar complex associated 4 homolog; Belongs to the CBF/MAK21 family.	Von Willebrand factor A domain containing 7.	0.490
SAPCD1	VWA7	ENSP00000411948	ENSP00000364840	Suppressor APC domain containing 1.	Von Willebrand factor A domain containing 7.	0.570
TMEM9B	CCNQ	ENSP00000433361	ENSP00000402949	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family.	Cyclin-Q; Activating cyclin for the cyclin-associated kinase CDK10. Belongs to the cyclin family. Cyclin-like FAM58 subfamily.	0.548
TMEM9B	DPY19L4	ENSP00000433361	ENSP00000389630	Transmembrane protein 9B; Enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways; Belongs to the TMEM9 family.	Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.	0.543