TMEM82 protein (human) - STRING interaction network

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TMEM82

Transmembrane protein 82. (343 aa)

Predicted Functional Partners:

FAM131C

0.624

SLC25A34

0.605

FBLIM1

0.567

SPATA3

0.523

CEP78

0.496

GUCA2B

0.478

CEP41

0.477

SH3BP4

0.477

CCDC163

0.477

ZNF638

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC163	TMEM82	ENSP00000487061	ENSP00000364938	Transmembrane protein CCDC163; Coiled-coil domain containing 163.	Transmembrane protein 82.	0.477
CEP41	CEP78	ENSP00000223208	ENSP00000365782	Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family.	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	0.471
CEP41	TMEM82	ENSP00000223208	ENSP00000364938	Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family.	Transmembrane protein 82.	0.477
CEP78	CEP41	ENSP00000365782	ENSP00000223208	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family.	0.471
CEP78	SH3BP4	ENSP00000365782	ENSP00000386862	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.	0.429
CEP78	SPATA3	ENSP00000365782	ENSP00000388895	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	Spermatogenesis-associated protein 3; Spermatogenesis associated 3.	0.512
CEP78	TMEM82	ENSP00000365782	ENSP00000364938	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	Transmembrane protein 82.	0.496
FAM131C	TMEM82	ENSP00000364814	ENSP00000364938	Protein FAM131C; Family with sequence similarity 131 member C.	Transmembrane protein 82.	0.624
FBLIM1	TMEM82	ENSP00000416387	ENSP00000364938	Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.	Transmembrane protein 82.	0.567
GUCA2B	TMEM82	ENSP00000361662	ENSP00000364938	Guanylate cyclase C-activating peptide 2; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.	Transmembrane protein 82.	0.478
SH3BP4	CEP78	ENSP00000386862	ENSP00000365782	SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	0.429
SH3BP4	TMEM82	ENSP00000386862	ENSP00000364938	SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.	Transmembrane protein 82.	0.477
SLC25A34	TMEM82	ENSP00000294454	ENSP00000364938	Solute carrier family 25 member 34.	Transmembrane protein 82.	0.605
SPATA3	CEP78	ENSP00000388895	ENSP00000365782	Spermatogenesis-associated protein 3; Spermatogenesis associated 3.	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	0.512
SPATA3	TMEM82	ENSP00000388895	ENSP00000364938	Spermatogenesis-associated protein 3; Spermatogenesis associated 3.	Transmembrane protein 82.	0.523
TMEM82	CCDC163	ENSP00000364938	ENSP00000487061	Transmembrane protein 82.	Transmembrane protein CCDC163; Coiled-coil domain containing 163.	0.477
TMEM82	CEP41	ENSP00000364938	ENSP00000223208	Transmembrane protein 82.	Centrosomal protein of 41 kDa; Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family.	0.477
TMEM82	CEP78	ENSP00000364938	ENSP00000365782	Transmembrane protein 82.	Centrosomal protein of 78 kDa; May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. May play a role in cilium biogenesis.	0.496
TMEM82	FAM131C	ENSP00000364938	ENSP00000364814	Transmembrane protein 82.	Protein FAM131C; Family with sequence similarity 131 member C.	0.624
TMEM82	FBLIM1	ENSP00000364938	ENSP00000416387	Transmembrane protein 82.	Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.	0.567