node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC4 | MKX | ENSP00000306410 | ENSP00000364946 | Armadillo repeat-containing protein 4; Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly. | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Belongs to the TALE/IRO homeobox family. | 0.547 |
BGN | COL1A1 | ENSP00000327336 | ENSP00000225964 | Biglycan; May be involved in collagen fiber assembly. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.974 |
BGN | DCN | ENSP00000327336 | ENSP00000052754 | Biglycan; May be involved in collagen fiber assembly. | Decorin; May affect the rate of fibrils formation. | 0.989 |
BGN | FMOD | ENSP00000327336 | ENSP00000347041 | Biglycan; May be involved in collagen fiber assembly. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.976 |
BGN | MKX | ENSP00000327336 | ENSP00000364946 | Biglycan; May be involved in collagen fiber assembly. | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Belongs to the TALE/IRO homeobox family. | 0.542 |
BGN | SCX | ENSP00000327336 | ENSP00000476384 | Biglycan; May be involved in collagen fiber assembly. | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages. | 0.412 |
BGN | TNMD | ENSP00000327336 | ENSP00000362122 | Biglycan; May be involved in collagen fiber assembly. | Tenomodulin; May be an angiogenesis inhibitor. | 0.673 |
COL1A1 | BGN | ENSP00000225964 | ENSP00000327336 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Biglycan; May be involved in collagen fiber assembly. | 0.974 |
COL1A1 | DCN | ENSP00000225964 | ENSP00000052754 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Decorin; May affect the rate of fibrils formation. | 0.923 |
COL1A1 | EGR1 | ENSP00000225964 | ENSP00000239938 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor forma [...] | 0.623 |
COL1A1 | FMOD | ENSP00000225964 | ENSP00000347041 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.792 |
COL1A1 | MKX | ENSP00000225964 | ENSP00000364946 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Belongs to the TALE/IRO homeobox family. | 0.602 |
COL1A1 | SCX | ENSP00000225964 | ENSP00000476384 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages. | 0.678 |
COL1A1 | SMAD3 | ENSP00000225964 | ENSP00000332973 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP- 1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and m [...] | 0.773 |
COL1A1 | TNMD | ENSP00000225964 | ENSP00000362122 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Tenomodulin; May be an angiogenesis inhibitor. | 0.774 |
DCN | BGN | ENSP00000052754 | ENSP00000327336 | Decorin; May affect the rate of fibrils formation. | Biglycan; May be involved in collagen fiber assembly. | 0.989 |
DCN | COL1A1 | ENSP00000052754 | ENSP00000225964 | Decorin; May affect the rate of fibrils formation. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.923 |
DCN | FMOD | ENSP00000052754 | ENSP00000347041 | Decorin; May affect the rate of fibrils formation. | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.938 |
DCN | MKX | ENSP00000052754 | ENSP00000364946 | Decorin; May affect the rate of fibrils formation. | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Belongs to the TALE/IRO homeobox family. | 0.632 |
DCN | SCX | ENSP00000052754 | ENSP00000476384 | Decorin; May affect the rate of fibrils formation. | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages. | 0.497 |