STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AADACL4Arylacetamide deacetylase-like 4; Arylacetamide deacetylase family (407 aa)    
Predicted Functional Partners:
AASDH
Acyl-CoA synthetase family member 4; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA; Acyl-CoA synthetase family
  
  
 0.538
AAED1
Thioredoxin-like protein AAED1; AhpC/TSA antioxidant enzyme domain containing 1; Belongs to the AAED1 family
      
 0.512
QTRTD1
Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA- ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine)
   
  
 0.484
A4GNT
Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity); Alpha 1,4-glycosyltransferases
      
 0.473
AAGAB
Alpha- and gamma-adaptin-binding protein p34; May be involved in endocytic recycling of growth factor receptors such as EGFR
      
 0.473
AAMDC
Mth938 domain-containing protein; May play a role in preadipocyte differentiation and adipogenesis; Belongs to the AAMDC family
      
 0.470
RNF148
Ring finger protein 148
   
  
 0.462
AARSD1
Alanyl-tRNA editing protein Aarsd1; Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)
      
 0.448
PLEKHO2
Pleckstrin homology domain containing O2
      
 0.444
AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively
   
  
 0.437
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (14%) [HD]