node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC158 | ZNF615 | ENSP00000373566 | ENSP00000471041 | Coiled-coil domain containing 158. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.457 |
CEACAM18 | ZNF615 | ENSP00000379738 | ENSP00000471041 | CEA cell adhesion molecule 18; Belongs to the immunoglobulin superfamily. CEA family. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.407 |
GIN1 | ZNF615 | ENSP00000381970 | ENSP00000471041 | Gypsy retrotransposon integrase 1. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.413 |
TRIM28 | ZNF235 | ENSP00000253024 | ENSP00000291182 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 235; May be involved in transcriptional regulation. | 0.679 |
TRIM28 | ZNF461 | ENSP00000253024 | ENSP00000467931 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.546 |
TRIM28 | ZNF613 | ENSP00000253024 | ENSP00000293471 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.522 |
TRIM28 | ZNF614 | ENSP00000253024 | ENSP00000270649 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 614; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
TRIM28 | ZNF615 | ENSP00000253024 | ENSP00000471041 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.522 |
ZNF235 | TRIM28 | ENSP00000291182 | ENSP00000253024 | Zinc finger protein 235; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.679 |
ZNF235 | ZNF615 | ENSP00000291182 | ENSP00000471041 | Zinc finger protein 235; May be involved in transcriptional regulation. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.559 |
ZNF260 | ZNF615 | ENSP00000429803 | ENSP00000471041 | Zinc finger protein 260; Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator (By similarity). | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.434 |
ZNF461 | TRIM28 | ENSP00000467931 | ENSP00000253024 | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.546 |
ZNF461 | ZNF615 | ENSP00000467931 | ENSP00000471041 | Zinc finger protein 461; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.796 |
ZNF613 | TRIM28 | ENSP00000293471 | ENSP00000253024 | Zinc finger protein 613; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.522 |
ZNF613 | ZNF615 | ENSP00000293471 | ENSP00000471041 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.498 |
ZNF614 | TRIM28 | ENSP00000270649 | ENSP00000253024 | Zinc finger protein 614; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.522 |
ZNF614 | ZNF615 | ENSP00000270649 | ENSP00000471041 | Zinc finger protein 614; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.519 |
ZNF615 | CCDC158 | ENSP00000471041 | ENSP00000373566 | Zinc finger protein 615; May be involved in transcriptional regulation. | Coiled-coil domain containing 158. | 0.457 |
ZNF615 | CEACAM18 | ENSP00000471041 | ENSP00000379738 | Zinc finger protein 615; May be involved in transcriptional regulation. | CEA cell adhesion molecule 18; Belongs to the immunoglobulin superfamily. CEA family. | 0.407 |
ZNF615 | GIN1 | ENSP00000471041 | ENSP00000381970 | Zinc finger protein 615; May be involved in transcriptional regulation. | Gypsy retrotransposon integrase 1. | 0.413 |