STRINGSTRING
SSX1 protein (human) - STRING interaction network
"SSX1" - Protein SSX1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSX1Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family (188 aa)    
Predicted Functional Partners:
SS18
Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation; BAF complex (418 aa)
           
  0.902
SSX2IP
Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...] (614 aa)
           
  0.779
ZNF117
Zinc finger protein 117; May be involved in transcriptional regulation; Zinc fingers C2H2-type (483 aa)
           
  0.742
ZNF83
Zinc finger protein 83; May be involved in transcriptional regulation; Zinc fingers C2H2-type (516 aa)
           
  0.719
MAGEC2
Melanoma-associated antigen C2; Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3-substrate complex; MAGE family (373 aa)
     
 
  0.708
MAGEC1
Melanoma-associated antigen C1; MAGE family member C1 (1142 aa)
     
   
  0.689
MAGEA1
Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes; MAGE family (309 aa)
     
   
  0.685
CTAG1A
Cancer/testis antigen 1A; Belongs to the CTAG/PCC1 family (180 aa)
           
  0.670
CTAG1B
Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family (180 aa)
           
  0.670
CTAG2
Cancer/testis antigen 2 (210 aa)
           
  0.670
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (13%) [HD]