node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C6orf132 | INSYN2B | ENSP00000341368 | ENSP00000366582 | Uncharacterized protein C6orf132; Chromosome 6 open reading frame 132. | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | 0.596 |
C6orf132 | TTC9 | ENSP00000341368 | ENSP00000256367 | Uncharacterized protein C6orf132; Chromosome 6 open reading frame 132. | Tetratricopeptide repeat domain 9; Belongs to the TTC9 family. | 0.581 |
EGFL6 | INSYN2B | ENSP00000369976 | ENSP00000366582 | Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). Belongs to the nephronectin family. | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | 0.423 |
EGFL6 | LRRC34 | ENSP00000369976 | ENSP00000414635 | Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). Belongs to the nephronectin family. | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | 0.405 |
EXPH5 | INSYN2B | ENSP00000265843 | ENSP00000366582 | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking. | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | 0.420 |
INSYN2B | C6orf132 | ENSP00000366582 | ENSP00000341368 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Uncharacterized protein C6orf132; Chromosome 6 open reading frame 132. | 0.596 |
INSYN2B | EGFL6 | ENSP00000366582 | ENSP00000369976 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). Belongs to the nephronectin family. | 0.423 |
INSYN2B | EXPH5 | ENSP00000366582 | ENSP00000265843 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking. | 0.420 |
INSYN2B | LRRC34 | ENSP00000366582 | ENSP00000414635 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | 0.607 |
INSYN2B | LRRIQ4 | ENSP00000366582 | ENSP00000342188 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Leucine rich repeats and IQ motif containing 4. | 0.485 |
INSYN2B | LYPD6 | ENSP00000366582 | ENSP00000334463 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Ly6/PLAUR domain-containing protein 6; Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs. Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity). | 0.628 |
INSYN2B | TMEM174 | ENSP00000366582 | ENSP00000296776 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Transmembrane protein 174. | 0.591 |
INSYN2B | TMEM72 | ENSP00000366582 | ENSP00000374234 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Transmembrane protein 72. | 0.434 |
INSYN2B | TTC9 | ENSP00000366582 | ENSP00000256367 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Tetratricopeptide repeat domain 9; Belongs to the TTC9 family. | 0.491 |
INSYN2B | ZNF28 | ENSP00000366582 | ENSP00000397693 | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | Zinc finger protein 28; May be involved in transcriptional regulation. | 0.452 |
LRRC34 | EGFL6 | ENSP00000414635 | ENSP00000369976 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | Epidermal growth factor-like protein 6; May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). Belongs to the nephronectin family. | 0.405 |
LRRC34 | INSYN2B | ENSP00000414635 | ENSP00000366582 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family. | 0.607 |
LRRC34 | LRRIQ4 | ENSP00000414635 | ENSP00000342188 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | Leucine rich repeats and IQ motif containing 4. | 0.730 |
LRRC34 | LYPD6 | ENSP00000414635 | ENSP00000334463 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | Ly6/PLAUR domain-containing protein 6; Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs. Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity). | 0.482 |
LRRC34 | TMEM174 | ENSP00000414635 | ENSP00000296776 | Leucine-rich repeat-containing protein 34; Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. | Transmembrane protein 174. | 0.429 |