STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD20A2Ankyrin repeat domain-containing protein 20A2. (823 aa)    
Predicted Functional Partners:
GOLGA6C
Golgin A6 family member C; Belongs to the GOLGA6 family.
   
 
 0.752
FOXD4L5
Forkhead box D4 like 5.
    
 
 0.658
ANKRD20A1
Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1.
  
 
0.633
ANKRD20A4
Ankyrin repeat domain-containing protein 20A4.
  
 
0.631
PDZRN3
E3 ubiquitin-protein ligase PDZRN3; E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.
    
 
 0.617
FOXD4L3
Forkhead box D4 like 3.
    
 
 0.615
ZNF595
Zinc finger protein 595; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.600
C2orf42
Uncharacterized protein C2orf42; Chromosome 2 open reading frame 42.
      
 0.579
DHRS4L2
Dehydrogenase/reductase SDR family member 4-like 2; Probable oxidoreductase.
    
 0.516
ZNF492
Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.504
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.