node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT2 | KRT38 | ENSP00000310861 | ENSP00000246646 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family. | 0.664 |
KRT2 | KRT40 | ENSP00000310861 | ENSP00000366984 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type I cytoskeletal 40; May play a role in late hair differentiation; Belongs to the intermediate filament family. | 0.513 |
KRT2 | KRT6A | ENSP00000310861 | ENSP00000369317 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | 0.445 |
KRT23 | KRT25 | ENSP00000209718 | ENSP00000310573 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.468 |
KRT23 | KRT26 | ENSP00000209718 | ENSP00000334798 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cytoskeletal 26; Keratin 26. | 0.463 |
KRT23 | KRT27 | ENSP00000209718 | ENSP00000301656 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | 0.457 |
KRT23 | KRT28 | ENSP00000209718 | ENSP00000305263 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs). | 0.447 |
KRT23 | KRT35 | ENSP00000209718 | ENSP00000377558 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family. | 0.432 |
KRT23 | KRT38 | ENSP00000209718 | ENSP00000246646 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family. | 0.443 |
KRT23 | KRT40 | ENSP00000209718 | ENSP00000366984 | Keratin, type I cytoskeletal 23; Keratin 23. | Keratin, type I cytoskeletal 40; May play a role in late hair differentiation; Belongs to the intermediate filament family. | 0.483 |
KRT25 | KRT23 | ENSP00000310573 | ENSP00000209718 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 23; Keratin 23. | 0.468 |
KRT25 | KRT26 | ENSP00000310573 | ENSP00000334798 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 26; Keratin 26. | 0.479 |
KRT25 | KRT27 | ENSP00000310573 | ENSP00000301656 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | 0.879 |
KRT25 | KRT28 | ENSP00000310573 | ENSP00000305263 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 28; Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs). | 0.582 |
KRT25 | KRT35 | ENSP00000310573 | ENSP00000377558 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family. | 0.720 |
KRT25 | KRT38 | ENSP00000310573 | ENSP00000246646 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family. | 0.522 |
KRT25 | KRT40 | ENSP00000310573 | ENSP00000366984 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 40; May play a role in late hair differentiation; Belongs to the intermediate filament family. | 0.505 |
KRT25 | KRTAP3-1 | ENSP00000310573 | ENSP00000375430 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.510 |
KRT26 | KRT23 | ENSP00000334798 | ENSP00000209718 | Keratin, type I cytoskeletal 26; Keratin 26. | Keratin, type I cytoskeletal 23; Keratin 23. | 0.463 |
KRT26 | KRT25 | ENSP00000334798 | ENSP00000310573 | Keratin, type I cytoskeletal 26; Keratin 26. | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.479 |