STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO48F-box protein 48. (155 aa)    
Predicted Functional Partners:
ZNF684
Zinc finger protein 684; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.624
ETAA1
Ewing's tumor-associated antigen 1; Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets.
    
 
 0.599
ECT2L
Epithelial cell-transforming sequence 2 oncogene-like; May act as a guanine nucleotide exchange factor (GEF).
      
 0.590
OR5AP2
Olfactory receptor 5AP2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
FBXO47
F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
      
 0.566
OR8B4
Olfactory receptor 8B4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.549
OR1L8
Olfactory receptor 1L8; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.511
FOXD4L6
Forkhead box D4 like 6.
      
 0.510
ZNF793
Zinc finger protein 793; May be involved in transcriptional regulation.
   
  
 0.500
PNO1
RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
      
 0.488
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.