STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf42Uncharacterized protein C12orf42; Chromosome 12 open reading frame 42. (360 aa)    
Predicted Functional Partners:
LRRC63
Leucine-rich repeat-containing protein 63; Leucine rich repeat containing 63.
      
 0.568
CCDC74B
Coiled-coil domain containing 74B.
      
 0.523
SPATA31A1
Spermatogenesis-associated protein 31A1; May play a role in spermatogenesis; Belongs to the SPATA31 family.
      
 0.506
ZNF577
Zinc finger protein 577; May be involved in transcriptional regulation.
      
 0.505
ANKRD60
Ankyrin repeat domain 60.
   
  
 0.482
ZNF571
Zinc finger protein 571; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.476
TTLL8
Protein monoglycylase TTLL8; Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity).
      
 0.454
ZNF730
Putative zinc finger protein 730; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.447
ALG1L
Putative glycosyltransferase ALG1-like; Putative glycosyltransferase.
      
 0.445
FAM47C
Putative protein FAM47C; Family with sequence similarity 47 member C; Belongs to the FAM47 family.
      
 0.431
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.