node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DYNLRB2 | MEIG1 | ENSP00000455791 | ENSP00000384334 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.553 |
FER1L6 | MEIG1 | ENSP00000428280 | ENSP00000384334 | Fer-1-like protein 6; Fer-1 like family member 6. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.580 |
MEIG1 | DYNLRB2 | ENSP00000384334 | ENSP00000455791 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. | 0.553 |
MEIG1 | FER1L6 | ENSP00000384334 | ENSP00000428280 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Fer-1-like protein 6; Fer-1 like family member 6. | 0.580 |
MEIG1 | PACRG | ENSP00000384334 | ENSP00000337946 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | 0.990 |
MEIG1 | PACRGL | ENSP00000384334 | ENSP00000423881 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | PACRG-like protein; Parkin coregulated like. | 0.794 |
MEIG1 | ROPN1 | ENSP00000384334 | ENSP00000184183 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.485 |
MEIG1 | ROPN1B | ENSP00000384334 | ENSP00000426271 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.483 |
MEIG1 | ROPN1L | ENSP00000384334 | ENSP00000421405 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. | 0.543 |
MEIG1 | SPAG16 | ENSP00000384334 | ENSP00000332592 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Sperm-associated antigen 16 protein; Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity). | 0.961 |
MEIG1 | SPAG6 | ENSP00000384334 | ENSP00000365811 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Sperm-associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. | 0.966 |
MEIG1 | TEKT2 | ENSP00000384334 | ENSP00000207457 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.509 |
PACRG | MEIG1 | ENSP00000337946 | ENSP00000384334 | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.990 |
PACRG | SPAG6 | ENSP00000337946 | ENSP00000365811 | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | Sperm-associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. | 0.549 |
PACRG | TEKT2 | ENSP00000337946 | ENSP00000207457 | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.876 |
PACRGL | MEIG1 | ENSP00000423881 | ENSP00000384334 | PACRG-like protein; Parkin coregulated like. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.794 |
ROPN1 | MEIG1 | ENSP00000184183 | ENSP00000384334 | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.485 |
ROPN1 | ROPN1B | ENSP00000184183 | ENSP00000426271 | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.884 |
ROPN1B | MEIG1 | ENSP00000426271 | ENSP00000384334 | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.483 |
ROPN1B | ROPN1 | ENSP00000426271 | ENSP00000184183 | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.884 |