node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTL9 | ACTRT2 | ENSP00000316674 | ENSP00000367658 | Actin-like protein 9; Actin like 9. | Actin related protein T2. | 0.579 |
ACTL9 | MYL1 | ENSP00000316674 | ENSP00000307280 | Actin-like protein 9; Actin like 9. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.505 |
ACTRT2 | ACTL9 | ENSP00000367658 | ENSP00000316674 | Actin related protein T2. | Actin-like protein 9; Actin like 9. | 0.579 |
ACTRT2 | C22orf23 | ENSP00000367658 | ENSP00000384667 | Actin related protein T2. | UPF0193 protein EVG1; Chromosome 22 open reading frame 23. | 0.511 |
ACTRT2 | CAPZA3 | ENSP00000367658 | ENSP00000326238 | Actin related protein T2. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.531 |
ACTRT2 | FAM186B | ENSP00000367658 | ENSP00000257894 | Actin related protein T2. | Protein FAM186B; Family with sequence similarity 186 member B. | 0.505 |
ACTRT2 | MYL1 | ENSP00000367658 | ENSP00000307280 | Actin related protein T2. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.505 |
ACTRT2 | OR10J1 | ENSP00000367658 | ENSP00000492902 | Actin related protein T2. | Olfactory receptor 10J1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.528 |
ACTRT2 | OR2T34 | ENSP00000367658 | ENSP00000330904 | Actin related protein T2. | Olfactory receptor 2T34; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.542 |
ACTRT2 | PDCL3 | ENSP00000367658 | ENSP00000264254 | Actin related protein T2. | Phosducin-like protein 3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity). Modulates the activation of caspases during apoptosis. | 0.522 |
ACTRT2 | PRDM16 | ENSP00000367658 | ENSP00000270722 | Actin related protein T2. | Histone-lysine N-methyltransferase PRDM16; Binds DNA and functions as a transcriptional regulator. Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation (By similarity). Likely to be one of the primary histone methyltransferases along with MECOM/PRDM3 that direct cytoplasmic [...] | 0.519 |
ACTRT2 | TSACC | ENSP00000367658 | ENSP00000357238 | Actin related protein T2. | TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family. | 0.518 |
C22orf23 | ACTRT2 | ENSP00000384667 | ENSP00000367658 | UPF0193 protein EVG1; Chromosome 22 open reading frame 23. | Actin related protein T2. | 0.511 |
C22orf23 | CAPZA3 | ENSP00000384667 | ENSP00000326238 | UPF0193 protein EVG1; Chromosome 22 open reading frame 23. | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | 0.477 |
C22orf23 | TSACC | ENSP00000384667 | ENSP00000357238 | UPF0193 protein EVG1; Chromosome 22 open reading frame 23. | TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family. | 0.663 |
CAPZA3 | ACTRT2 | ENSP00000326238 | ENSP00000367658 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | Actin related protein T2. | 0.531 |
CAPZA3 | C22orf23 | ENSP00000326238 | ENSP00000384667 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity). | UPF0193 protein EVG1; Chromosome 22 open reading frame 23. | 0.477 |
FAM186B | ACTRT2 | ENSP00000257894 | ENSP00000367658 | Protein FAM186B; Family with sequence similarity 186 member B. | Actin related protein T2. | 0.505 |
MYL1 | ACTL9 | ENSP00000307280 | ENSP00000316674 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Actin-like protein 9; Actin like 9. | 0.505 |
MYL1 | ACTRT2 | ENSP00000307280 | ENSP00000367658 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Actin related protein T2. | 0.505 |