STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LANCL3LanC-like protein 3; LanC like 3. (420 aa)    
Predicted Functional Partners:
PRRG1
Transmembrane gamma-carboxyglutamic acid protein 1; Proline rich and Gla domain 1.
   
  
 0.583
MAGEB16
Melanoma-associated antigen B16; MAGE family member B16.
      
 0.538
DYNLT3
Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity); Belongs to the dynein light chain Tctex-type family.
   
  
 0.487
OR10H4
Olfactory receptor 10H4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.477
CFAP47
Cilia and flagella associated protein 47.
   
  
 0.471
XK
Membrane transport protein XK; May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
 
 
  
 0.458
FAM47B
Protein FAM47B; Family with sequence similarity 47 member B; Belongs to the FAM47 family.
      
 0.436
SYTL5
Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.
   
  
 0.430
ECD
Protein ecdysoneless homolog; Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with th [...]
      
 0.418
C12orf43
Protein CUSTOS; Plays a role in the regulation of Wnt signaling pathway during early development.
      
 0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.