node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DENND2C | SYCE1L | ENSP00000376955 | ENSP00000367911 | DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.412 |
DENND2C | ZNF567 | ENSP00000376955 | ENSP00000441838 | DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. | Zinc finger protein 567; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.419 |
MON1B | SYCE1L | ENSP00000248248 | ENSP00000367911 | MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.543 |
MZT2B | SYCE1L | ENSP00000386419 | ENSP00000367911 | Mitotic spindle organizing protein 2B. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.453 |
RAD21 | SYCE1L | ENSP00000297338 | ENSP00000367911 | Double-strand-break repair protein rad21 homolog; [Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis. In interphase, cohesins may function in the control of gene expression by binding to n [...] | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.417 |
RAD21 | SYCE2 | ENSP00000297338 | ENSP00000293695 | Double-strand-break repair protein rad21 homolog; [Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis. In interphase, cohesins may function in the control of gene expression by binding to n [...] | Synaptonemal complex central element protein 2; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). Belongs to the SYCE family. | 0.662 |
SYCE1L | DENND2C | ENSP00000367911 | ENSP00000376955 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. | 0.412 |
SYCE1L | MON1B | ENSP00000367911 | ENSP00000248248 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family. | 0.543 |
SYCE1L | MZT2B | ENSP00000367911 | ENSP00000386419 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Mitotic spindle organizing protein 2B. | 0.453 |
SYCE1L | RAD21 | ENSP00000367911 | ENSP00000297338 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Double-strand-break repair protein rad21 homolog; [Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis. In interphase, cohesins may function in the control of gene expression by binding to n [...] | 0.417 |
SYCE1L | SYCE2 | ENSP00000367911 | ENSP00000293695 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Synaptonemal complex central element protein 2; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). Belongs to the SYCE family. | 0.512 |
SYCE1L | URB2 | ENSP00000367911 | ENSP00000258243 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | URB2 ribosome biogenesis homolog. | 0.425 |
SYCE1L | VAT1L | ENSP00000367911 | ENSP00000303129 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Synaptic vesicle membrane protein VAT-1 homolog-like; Vesicle amine transport 1 like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.498 |
SYCE1L | ZNF567 | ENSP00000367911 | ENSP00000441838 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Zinc finger protein 567; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.490 |
SYCE1L | ZNF775 | ENSP00000367911 | ENSP00000330838 | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | Zinc finger protein 775; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.449 |
SYCE2 | RAD21 | ENSP00000293695 | ENSP00000297338 | Synaptonemal complex central element protein 2; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). Belongs to the SYCE family. | Double-strand-break repair protein rad21 homolog; [Double-strand-break repair protein rad21 homolog]: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis. In interphase, cohesins may function in the control of gene expression by binding to n [...] | 0.662 |
SYCE2 | SYCE1L | ENSP00000293695 | ENSP00000367911 | Synaptonemal complex central element protein 2; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). Belongs to the SYCE family. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.512 |
URB2 | SYCE1L | ENSP00000258243 | ENSP00000367911 | URB2 ribosome biogenesis homolog. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.425 |
URB2 | ZNF567 | ENSP00000258243 | ENSP00000441838 | URB2 ribosome biogenesis homolog. | Zinc finger protein 567; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.432 |
VAT1L | SYCE1L | ENSP00000303129 | ENSP00000367911 | Synaptic vesicle membrane protein VAT-1 homolog-like; Vesicle amine transport 1 like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | Synaptonemal complex central element protein 1-like; May be involved in meiosis. | 0.498 |