STRINGSTRING
SHROOM1 protein (human) - STRING interaction network
"SHROOM1" - Protein Shroom1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHROOM1Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation (852 aa)    
Predicted Functional Partners:
SOWAHA
Ankyrin repeat domain-containing protein SOWAHA; Sosondowah ankyrin repeat domain family member A; Belongs to the SOWAH family (549 aa)
     
   
  0.726
APEX1
DNA-(apurinic or apyrimidinic site) lyase; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5’-deoxyribo [...] (318 aa)
           
  0.629
NYX
Nyctalopin (481 aa)
       
      0.540
SMIM5
Small integral membrane protein 5 (77 aa)
           
  0.530
PHLDB3
Pleckstrin homology like domain family B member 3 (640 aa)
           
  0.522
FANK1
Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing (345 aa)
           
  0.518
PRSS48
Serine protease 48; Belongs to the peptidase S1 family (328 aa)
           
  0.515
UBXN8
UBX domain-containing protein 8; Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction; UBX domain containing (270 aa)
           
  0.506
GRXCR2
Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Deafness associated genes (248 aa)
           
  0.502
OR11G2
Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11 (345 aa)
           
  0.471
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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