node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | LRRN4 | ENSP00000340688 | ENSP00000368135 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.514 |
ADGRL2 | LRRN4 | ENSP00000359765 | ENSP00000368135 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.515 |
ADGRL3 | LRRN4 | ENSP00000422533 | ENSP00000368135 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.514 |
GPM6A | LRRN4 | ENSP00000280187 | ENSP00000368135 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and re [...] | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.454 |
GPM6A | UPK3B | ENSP00000280187 | ENSP00000334938 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and re [...] | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | 0.515 |
HIGD1B | LRRN4 | ENSP00000253410 | ENSP00000368135 | HIG1 hypoxia inducible domain family member 1B. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.402 |
LRRN4 | ADGRL1 | ENSP00000368135 | ENSP00000340688 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.514 |
LRRN4 | ADGRL2 | ENSP00000368135 | ENSP00000359765 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.515 |
LRRN4 | ADGRL3 | ENSP00000368135 | ENSP00000422533 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.514 |
LRRN4 | GPM6A | ENSP00000368135 | ENSP00000280187 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and re [...] | 0.454 |
LRRN4 | HIGD1B | ENSP00000368135 | ENSP00000253410 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | HIG1 hypoxia inducible domain family member 1B. | 0.402 |
LRRN4 | MSLN | ENSP00000368135 | ENSP00000372313 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion; Belongs to the mesothelin family. | 0.489 |
LRRN4 | NKAIN4 | ENSP00000368135 | ENSP00000359340 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | 0.482 |
LRRN4 | UPK3B | ENSP00000368135 | ENSP00000334938 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | 0.738 |
MSLN | LRRN4 | ENSP00000372313 | ENSP00000368135 | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion; Belongs to the mesothelin family. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.489 |
MSLN | UPK3B | ENSP00000372313 | ENSP00000334938 | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion; Belongs to the mesothelin family. | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | 0.659 |
NKAIN4 | LRRN4 | ENSP00000359340 | ENSP00000368135 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.482 |
NKAIN4 | UPK3B | ENSP00000359340 | ENSP00000334938 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | 0.441 |
UPK3B | GPM6A | ENSP00000334938 | ENSP00000280187 | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and re [...] | 0.515 |
UPK3B | LRRN4 | ENSP00000334938 | ENSP00000368135 | Putative postmeiotic segregation increased 2-like protein 11; Uroplakin 3B. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.738 |