node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID3A | ARID3B | ENSP00000263620 | ENSP00000477878 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | 0.814 |
ARID3A | ARID3C | ENSP00000263620 | ENSP00000368189 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | 0.716 |
ARID3A | MYSM1 | ENSP00000263620 | ENSP00000418734 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis [...] | 0.426 |
ARID3A | PBRM1 | ENSP00000263620 | ENSP00000386593 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | Protein polybromo-1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. | 0.533 |
ARID3A | SMARCB1 | ENSP00000263620 | ENSP00000340883 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.573 |
ARID3B | ARID3A | ENSP00000477878 | ENSP00000263620 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | 0.814 |
ARID3B | ARID3C | ENSP00000477878 | ENSP00000368189 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | 0.551 |
ARID3B | MYSM1 | ENSP00000477878 | ENSP00000418734 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis [...] | 0.431 |
ARID3B | PBRM1 | ENSP00000477878 | ENSP00000386593 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | Protein polybromo-1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. | 0.526 |
ARID3B | SMARCB1 | ENSP00000477878 | ENSP00000340883 | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.517 |
ARID3C | ARID3A | ENSP00000368189 | ENSP00000263620 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. | 0.716 |
ARID3C | ARID3B | ENSP00000368189 | ENSP00000477878 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | AT-rich interactive domain-containing protein 3B; Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. | 0.551 |
ARID3C | BRK1 | ENSP00000368189 | ENSP00000432472 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | 0.449 |
ARID3C | CROCC2 | ENSP00000368189 | ENSP00000397968 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Ciliary rootlet coiled-coil, rootletin family member 2; Belongs to the rootletin family. | 0.466 |
ARID3C | DCTN3 | ENSP00000368189 | ENSP00000259632 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis. | 0.558 |
ARID3C | FAM205A | ENSP00000368189 | ENSP00000417711 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Protein FAM205A; Family with sequence similarity 205 member A. | 0.433 |
ARID3C | FAM219A | ENSP00000368189 | ENSP00000499069 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Protein FAM219A; Family with sequence similarity 219 member A. | 0.448 |
ARID3C | MYSM1 | ENSP00000368189 | ENSP00000418734 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis [...] | 0.426 |
ARID3C | PBRM1 | ENSP00000368189 | ENSP00000386593 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | Protein polybromo-1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. | 0.526 |
ARID3C | SMARCB1 | ENSP00000368189 | ENSP00000340883 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain 3C. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.540 |