MAGEB2 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPATCH4	MAGEB2	ENSP00000396441	ENSP00000368273	G-patch domain containing 4.	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	0.811
GPATCH4	PPAN-P2RY11	ENSP00000396441	ENSP00000377385	G-patch domain containing 4.	PPAN-P2RY11 readthrough; Belongs to the G-protein coupled receptor 1 family.	0.493
GPATCH4	RPL10	ENSP00000396441	ENSP00000413436	G-patch domain containing 4.	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.	0.824
GPATCH4	RPL26L1	ENSP00000396441	ENSP00000428223	G-patch domain containing 4.	Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family.	0.846
GPATCH4	RPL3	ENSP00000396441	ENSP00000346001	G-patch domain containing 4.	60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.	0.816
MAGEB10	MAGEB2	ENSP00000368304	ENSP00000368273	Melanoma-associated antigen B10; MAGE family member B10.	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	0.663
MAGEB10	MAGEB4	ENSP00000368304	ENSP00000368266	Melanoma-associated antigen B10; MAGE family member B10.	Melanoma-associated antigen B4; MAGE family member B4.	0.967
MAGEB10	MAGEC2	ENSP00000368304	ENSP00000354660	Melanoma-associated antigen B10; MAGE family member B10.	Melanoma-associated antigen C2; Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.	0.942
MAGEB10	RPL26L1	ENSP00000368304	ENSP00000428223	Melanoma-associated antigen B10; MAGE family member B10.	Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family.	0.855
MAGEB10	RPL3	ENSP00000368304	ENSP00000346001	Melanoma-associated antigen B10; MAGE family member B10.	60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.	0.890
MAGEB2	GPATCH4	ENSP00000368273	ENSP00000396441	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	G-patch domain containing 4.	0.811
MAGEB2	MAGEB10	ENSP00000368273	ENSP00000368304	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	Melanoma-associated antigen B10; MAGE family member B10.	0.663
MAGEB2	MAGEB4	ENSP00000368273	ENSP00000368266	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	Melanoma-associated antigen B4; MAGE family member B4.	0.636
MAGEB2	MAGEC2	ENSP00000368273	ENSP00000354660	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	Melanoma-associated antigen C2; Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.	0.702
MAGEB2	PPAN-P2RY11	ENSP00000368273	ENSP00000377385	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	PPAN-P2RY11 readthrough; Belongs to the G-protein coupled receptor 1 family.	0.811
MAGEB2	RPL10	ENSP00000368273	ENSP00000413436	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.	0.811
MAGEB2	RPL10L	ENSP00000368273	ENSP00000298283	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	60S ribosomal protein L10-like; May play a role in compensating for the inactivated X-linked gene during spermatogenesis.	0.999
MAGEB2	RPL26L1	ENSP00000368273	ENSP00000428223	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family.	0.811
MAGEB2	RPL3	ENSP00000368273	ENSP00000346001	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.	0.820
MAGEB2	RPL36AL	ENSP00000368273	ENSP00000346012	Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.	Ribosomal protein L36a like; Belongs to the eukaryotic ribosomal protein eL42 family.	0.820