C11orf91 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf91	COMMD9	ENSP00000368296	ENSP00000263401	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	COMM domain-containing protein 9; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF- kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride- sensitive sodium channel (ENaC) subunits.	0.430
C11orf91	FBXO3	ENSP00000368296	ENSP00000265651	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	F-box only protein 3; Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.	0.550
C11orf91	OR13C5	ENSP00000368296	ENSP00000363911	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	Olfactory receptor 13C5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.441
C11orf91	TCP11L1	ENSP00000368296	ENSP00000335595	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.419
C11orf91	TRAPPC6B	ENSP00000368296	ENSP00000330289	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable).	0.486
COMMD9	C11orf91	ENSP00000263401	ENSP00000368296	COMM domain-containing protein 9; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF- kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride- sensitive sodium channel (ENaC) subunits.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.430
COMMD9	TCP11L1	ENSP00000263401	ENSP00000335595	COMM domain-containing protein 9; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF- kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride- sensitive sodium channel (ENaC) subunits.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.444
FBXO3	C11orf91	ENSP00000265651	ENSP00000368296	F-box only protein 3; Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.550
OR13C5	C11orf91	ENSP00000363911	ENSP00000368296	Olfactory receptor 13C5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.441
TCP11L1	C11orf91	ENSP00000335595	ENSP00000368296	T-complex protein 11-like protein 1; T-complex 11 like 1.	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.419
TCP11L1	COMMD9	ENSP00000335595	ENSP00000263401	T-complex protein 11-like protein 1; T-complex 11 like 1.	COMM domain-containing protein 9; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF- kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride- sensitive sodium channel (ENaC) subunits.	0.444
TRAPPC6B	C11orf91	ENSP00000330289	ENSP00000368296	Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable).	Uncharacterized protein C11orf91; Chromosome 11 open reading frame 91.	0.486