node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETFRF1 | FMC1 | ENSP00000450584 | ENSP00000297534 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | 0.596 |
ETFRF1 | LYRM1 | ENSP00000450584 | ENSP00000379367 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family. | 0.821 |
ETFRF1 | LYRM2 | ENSP00000450584 | ENSP00000430025 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | LYR motif containing 2. | 0.793 |
ETFRF1 | LYRM4 | ENSP00000450584 | ENSP00000443900 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; Belongs to the complex I LYR family. | 0.706 |
ETFRF1 | LYRM7 | ENSP00000450584 | ENSP00000368688 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. | 0.730 |
ETFRF1 | LYRM9 | ENSP00000450584 | ENSP00000368397 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | LYR motif containing 9; Belongs to the complex I LYR family. LYRM9 subfamily. | 0.707 |
ETFRF1 | NDUFA6 | ENSP00000450584 | ENSP00000482543 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Required for proper complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.441 |
ETFRF1 | NDUFAB1 | ENSP00000450584 | ENSP00000458770 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. | 0.948 |
ETFRF1 | NDUFB9 | ENSP00000450584 | ENSP00000276689 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.585 |
ETFRF1 | SDHAF1 | ENSP00000450584 | ENSP00000368165 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Succinate dehydrogenase assembly factor 1, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDH [...] | 0.564 |
FMC1 | ETFRF1 | ENSP00000297534 | ENSP00000450584 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | 0.596 |
FMC1 | LYRM1 | ENSP00000297534 | ENSP00000379367 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family. | 0.595 |
FMC1 | LYRM2 | ENSP00000297534 | ENSP00000430025 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | LYR motif containing 2. | 0.583 |
FMC1 | LYRM4 | ENSP00000297534 | ENSP00000443900 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; Belongs to the complex I LYR family. | 0.435 |
FMC1 | LYRM7 | ENSP00000297534 | ENSP00000368688 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. | 0.537 |
FMC1 | LYRM9 | ENSP00000297534 | ENSP00000368397 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | LYR motif containing 9; Belongs to the complex I LYR family. LYRM9 subfamily. | 0.604 |
FMC1 | NDUFA6 | ENSP00000297534 | ENSP00000482543 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Required for proper complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.447 |
FMC1 | NDUFB9 | ENSP00000297534 | ENSP00000276689 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.438 |
FMC1 | SDHAF1 | ENSP00000297534 | ENSP00000368165 | Protein FMC1 homolog; Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) ; Belongs to the FMC1 family. | Succinate dehydrogenase assembly factor 1, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDH [...] | 0.532 |
LYRM1 | ETFRF1 | ENSP00000379367 | ENSP00000450584 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family. | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | 0.821 |