node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FPGT-TNNI3K | LINGO2 | ENSP00000450895 | ENSP00000369328 | FPGT-TNNI3K readthrough. | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | 0.572 |
FPGT-TNNI3K | MTIF3 | ENSP00000450895 | ENSP00000370508 | FPGT-TNNI3K readthrough. | Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. | 0.596 |
FPGT-TNNI3K | POC5 | ENSP00000450895 | ENSP00000410216 | FPGT-TNNI3K readthrough. | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family. | 0.596 |
FPGT-TNNI3K | SEC16B | ENSP00000450895 | ENSP00000308339 | FPGT-TNNI3K readthrough. | Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family. | 0.719 |
FPGT-TNNI3K | TMEM160 | ENSP00000450895 | ENSP00000253047 | FPGT-TNNI3K readthrough. | Transmembrane protein 160. | 0.599 |
FPGT-TNNI3K | TNNI3K | ENSP00000450895 | ENSP00000322251 | FPGT-TNNI3K readthrough. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.902 |
LINGO2 | FPGT-TNNI3K | ENSP00000369328 | ENSP00000450895 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | FPGT-TNNI3K readthrough. | 0.572 |
LINGO2 | MOB3B | ENSP00000369328 | ENSP00000262244 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | MOB kinase activator 3B; Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.614 |
LINGO2 | MTIF3 | ENSP00000369328 | ENSP00000370508 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. | 0.584 |
LINGO2 | POC5 | ENSP00000369328 | ENSP00000410216 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family. | 0.580 |
LINGO2 | RTN4R | ENSP00000369328 | ENSP00000043402 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Reticulon-4 receptor; Receptor for RTN4, OMG and MAG. Functions as receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as receptor for chondroitin sulfate proteoglycans (By similarity). Can also bind heparin (By similarity). Intracellular signaling cascades are triggered via the coreceptor NGFR. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. Mediates axonal growth inhibition. Plays a role in regulating axon regeneration and neuronal plasticity in the adult central nervous system. Plays a role in postnatal brain develo [...] | 0.734 |
LINGO2 | SEC16B | ENSP00000369328 | ENSP00000308339 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family. | 0.576 |
LINGO2 | TBPL1 | ENSP00000369328 | ENSP00000237264 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box. | 0.598 |
LINGO2 | TFF3 | ENSP00000369328 | ENSP00000430690 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). | 0.741 |
LINGO2 | TMEM160 | ENSP00000369328 | ENSP00000253047 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Transmembrane protein 160. | 0.570 |
LINGO2 | TNNI3K | ENSP00000369328 | ENSP00000322251 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.560 |
MOB3B | LINGO2 | ENSP00000262244 | ENSP00000369328 | MOB kinase activator 3B; Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | 0.614 |
MTIF3 | FPGT-TNNI3K | ENSP00000370508 | ENSP00000450895 | Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. | FPGT-TNNI3K readthrough. | 0.596 |
MTIF3 | LINGO2 | ENSP00000370508 | ENSP00000369328 | Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine rich repeat and Ig domain containing 2. | 0.584 |
MTIF3 | POC5 | ENSP00000370508 | ENSP00000410216 | Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family. | 0.550 |