STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A35Solute carrier family 25 member 35; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa)    
Predicted Functional Partners:
SLC25A53
Solute carrier family 25 member 53.
      
 0.613
SLC25A39
Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.571
SLC25A51
Solute carrier family 25 member 51.
      
 0.531
SLC25A41
Solute carrier family 25 member 41.
   
  
 0.498
CPSF4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein; Cleavage and polyadenylation specific factor 4 like; Belongs to the CPSF4/YTH1 family.
   
  
 0.485
SLC38A8
Putative sodium-coupled neutral amino acid transporter 8; Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family.
      
 0.455
SLC25A52
Solute carrier family 25 member 52.
      
 0.432
TRIL
TLR4 interactor with leucine rich repeats; Component of the TLR4 signaling complex. Mediates the innate immune response to bacterial lipopolysaccharide (LPS) leading to cytokine secretion.
      
 0.430
SDF2
Stromal cell derived factor 2.
   
  
 0.417
SVOPL
Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily.
      
 0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.