STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM50BProtein FAM50B; Family with sequence similarity 50 member B. (325 aa)    
Predicted Functional Partners:
ZDBF2
DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2.
      
 0.607
MCTS2P
Malignant T-cell-amplified sequence; MCTS family member 2, pseudogene.
      
 0.591
DIRAS3
GTP-binding protein Di-Ras3; DIRAS family GTPase 3.
   
 
 0.583
MEST
Mesoderm-specific transcript homolog protein; Mesoderm specific transcript; Belongs to the AB hydrolase superfamily.
    
 
 0.578
NAP1L5
Nucleosome assembly protein 1 like 5.
   
  
 0.534
PLAGL1
Zinc finger protein PLAGL1; Acts as a transcriptional activator. Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide.
    
 
 0.533
PXDC1
PX domain containing 1.
   
  
 0.518
ZNF597
Zinc finger protein 597; May be involved in transcriptional regulation.
   
 
 0.510
RPP25L
Ribonuclease P protein subunit p25-like protein; May be a component of ribonuclease P or MRP.
   
  
 0.506
WDR20
WD repeat-containing protein 20; Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12. Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme.
   
 
 0.495
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.