STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB136Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family. (78 aa)    
Predicted Functional Partners:
DEFB130B
Defensin beta 130B.
   
 
 0.678
DEFB135
Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.671
DEFB134
Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.669
DEFB130A
Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity.
     
 0.662
DEFB119
Defensin beta 119.
     
 0.661
DEFB110
Beta-defensin 110; Has antibacterial activity.
   
 
 0.636
DEFB128
Beta-defensin 128; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.616
DEFB116
Beta-defensin 116; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.601
DEFB113
Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.594
DEFB124
Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.591
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.