RNF215 protein (human) - STRING interaction network

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Score

RNF215

Ring finger protein 215. (377 aa)

Predicted Functional Partners:

COG6

0.695

TMPRSS12

0.666

COG5

0.641

ERGIC2

0.595

ZNF10

0.586

COG3

0.578

COG2

0.563

COG7

0.555

ASB8

0.552

CDC42

0.550

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB8	RNF215	ENSP00000445622	ENSP00000371800	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Ring finger protein 215.	0.552
CDC42	COG2	ENSP00000497733	ENSP00000355629	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	0.545
CDC42	COG3	ENSP00000497733	ENSP00000258654	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	0.590
CDC42	COG5	ENSP00000497733	ENSP00000297135	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	0.559
CDC42	COG6	ENSP00000497733	ENSP00000397441	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.	0.600
CDC42	COG7	ENSP00000497733	ENSP00000305442	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.575
CDC42	RNF215	ENSP00000497733	ENSP00000371800	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	Ring finger protein 215.	0.550
COG2	CDC42	ENSP00000355629	ENSP00000497733	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	0.545
COG2	COG3	ENSP00000355629	ENSP00000258654	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	0.999
COG2	COG5	ENSP00000355629	ENSP00000297135	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	0.999
COG2	COG6	ENSP00000355629	ENSP00000397441	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.	0.999
COG2	COG7	ENSP00000355629	ENSP00000305442	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.999
COG2	RNF215	ENSP00000355629	ENSP00000371800	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Ring finger protein 215.	0.563
COG3	CDC42	ENSP00000258654	ENSP00000497733	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	0.590
COG3	COG2	ENSP00000258654	ENSP00000355629	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	0.999
COG3	COG5	ENSP00000258654	ENSP00000297135	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	0.999
COG3	COG6	ENSP00000258654	ENSP00000397441	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.	0.999
COG3	COG7	ENSP00000258654	ENSP00000305442	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.999
COG3	RNF215	ENSP00000258654	ENSP00000371800	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	Ring finger protein 215.	0.578
COG5	CDC42	ENSP00000297135	ENSP00000497733	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections. Required for DOCK10-med [...]	0.559