RNF215 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD61	FAM110D	ENSP00000386502	ENSP00000363386	Ankyrin repeat domain 61.	Protein FAM110D; Family with sequence similarity 110 member D; Belongs to the FAM110 family.	0.665
ANKRD61	RNF215	ENSP00000386502	ENSP00000371800	Ankyrin repeat domain 61.	Ring finger protein 215.	0.521
ASB8	RNF215	ENSP00000445622	ENSP00000371800	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Ring finger protein 215.	0.532
ASB8	UBOX5	ENSP00000445622	ENSP00000217173	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	RING finger protein 37; May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates.	0.432
CCDC157	RNF215	ENSP00000385357	ENSP00000371800	Coiled-coil domain containing 157.	Ring finger protein 215.	0.462
ERGIC2	RNF215	ENSP00000353270	ENSP00000371800	Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.	Ring finger protein 215.	0.570
ERGIC2	TMPRSS12	ENSP00000353270	ENSP00000381476	Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.	Transmembrane serine protease 12; Belongs to the peptidase S1 family.	0.549
ERGIC2	ZNF10	ENSP00000353270	ENSP00000248211	Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.	Zinc finger protein 10; May be involved in transcriptional regulation.	0.476
FAM110D	ANKRD61	ENSP00000363386	ENSP00000386502	Protein FAM110D; Family with sequence similarity 110 member D; Belongs to the FAM110 family.	Ankyrin repeat domain 61.	0.665
FAM110D	RNF215	ENSP00000363386	ENSP00000371800	Protein FAM110D; Family with sequence similarity 110 member D; Belongs to the FAM110 family.	Ring finger protein 215.	0.479
ITFG2	RNF215	ENSP00000228799	ENSP00000371800	KICSTOR complex protein ITFG2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.	Ring finger protein 215.	0.473
KCNC4	RNF215	ENSP00000358802	ENSP00000371800	Potassium voltage-gated channel subfamily C member 4; This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.	Ring finger protein 215.	0.580
RNF215	ANKRD61	ENSP00000371800	ENSP00000386502	Ring finger protein 215.	Ankyrin repeat domain 61.	0.521
RNF215	ASB8	ENSP00000371800	ENSP00000445622	Ring finger protein 215.	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.532
RNF215	CCDC157	ENSP00000371800	ENSP00000385357	Ring finger protein 215.	Coiled-coil domain containing 157.	0.462
RNF215	ERGIC2	ENSP00000371800	ENSP00000353270	Ring finger protein 215.	Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.	0.570
RNF215	FAM110D	ENSP00000371800	ENSP00000363386	Ring finger protein 215.	Protein FAM110D; Family with sequence similarity 110 member D; Belongs to the FAM110 family.	0.479
RNF215	ITFG2	ENSP00000371800	ENSP00000228799	Ring finger protein 215.	KICSTOR complex protein ITFG2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.	0.473
RNF215	KCNC4	ENSP00000371800	ENSP00000358802	Ring finger protein 215.	Potassium voltage-gated channel subfamily C member 4; This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.	0.580
RNF215	TMPRSS12	ENSP00000371800	ENSP00000381476	Ring finger protein 215.	Transmembrane serine protease 12; Belongs to the peptidase S1 family.	0.650