FOXD4 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLAT	FOXD4	ENSP00000280346	ENSP00000371940	Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Forkhead box D4.	0.959
DLAT	PDHA1	ENSP00000280346	ENSP00000369134	Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.999
DLAT	PDHB	ENSP00000280346	ENSP00000307241	Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.999
DLAT	PDHX	ENSP00000280346	ENSP00000227868	Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Pyruvate dehydrogenase protein X component, mitochondrial; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.	0.999
FOXD4	DLAT	ENSP00000371940	ENSP00000280346	Forkhead box D4.	Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.959
FOXD4	FOXD4L1	ENSP00000371940	ENSP00000302756	Forkhead box D4.	Forkhead box D4 like 1.	0.997
FOXD4	FOXD4L3	ENSP00000371940	ENSP00000341961	Forkhead box D4.	Forkhead box D4 like 3.	0.943
FOXD4	FOXD4L4	ENSP00000371940	ENSP00000366630	Forkhead box D4.	Forkhead box D4 like 4.	0.919
FOXD4	FOXD4L5	ENSP00000371940	ENSP00000366637	Forkhead box D4.	Forkhead box D4 like 5.	0.941
FOXD4	FOXD4L6	ENSP00000371940	ENSP00000484875	Forkhead box D4.	Forkhead box D4 like 6.	0.941
FOXD4	PDHA1	ENSP00000371940	ENSP00000369134	Forkhead box D4.	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.925
FOXD4	PDHB	ENSP00000371940	ENSP00000307241	Forkhead box D4.	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.946
FOXD4	PDHX	ENSP00000371940	ENSP00000227868	Forkhead box D4.	Pyruvate dehydrogenase protein X component, mitochondrial; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.	0.913
FOXD4	PPP2R1B	ENSP00000371940	ENSP00000311344	Forkhead box D4.	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.	0.947
FOXD4L1	FOXD4	ENSP00000302756	ENSP00000371940	Forkhead box D4 like 1.	Forkhead box D4.	0.997
FOXD4L1	FOXD4L3	ENSP00000302756	ENSP00000341961	Forkhead box D4 like 1.	Forkhead box D4 like 3.	0.944
FOXD4L1	FOXD4L4	ENSP00000302756	ENSP00000366630	Forkhead box D4 like 1.	Forkhead box D4 like 4.	0.921
FOXD4L1	FOXD4L5	ENSP00000302756	ENSP00000366637	Forkhead box D4 like 1.	Forkhead box D4 like 5.	0.942
FOXD4L1	FOXD4L6	ENSP00000302756	ENSP00000484875	Forkhead box D4 like 1.	Forkhead box D4 like 6.	0.942
FOXD4L3	FOXD4	ENSP00000341961	ENSP00000371940	Forkhead box D4 like 3.	Forkhead box D4.	0.943