node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD12 | LRRC30 | ENSP00000262126 | ENSP00000372959 | Ankyrin repeat domain-containing protein 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.583 |
ASB10 | ASB12 | ENSP00000391137 | ENSP00000355195 | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.466 |
ASB10 | LRRC14B | ENSP00000391137 | ENSP00000327675 | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | 0.440 |
ASB10 | LRRC20 | ENSP00000391137 | ENSP00000348043 | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20. | 0.401 |
ASB10 | LRRC30 | ENSP00000391137 | ENSP00000372959 | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.544 |
ASB12 | ASB10 | ENSP00000355195 | ENSP00000391137 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.466 |
ASB12 | LRRC14B | ENSP00000355195 | ENSP00000327675 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | 0.585 |
ASB12 | LRRC20 | ENSP00000355195 | ENSP00000348043 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20. | 0.552 |
ASB12 | LRRC30 | ENSP00000355195 | ENSP00000372959 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.608 |
ATP1B4 | CHRNA1 | ENSP00000218008 | ENSP00000261007 | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit; Belongs to the X(+)/potassium ATPases subunit beta family. | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.517 |
ATP1B4 | LRRC30 | ENSP00000218008 | ENSP00000372959 | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit; Belongs to the X(+)/potassium ATPases subunit beta family. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.622 |
CDNF | LRRC30 | ENSP00000419395 | ENSP00000372959 | Cerebral dopamine neurotrophic factor; Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.595 |
CHRNA1 | ATP1B4 | ENSP00000261007 | ENSP00000218008 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.517 |
CHRNA1 | LRRC30 | ENSP00000261007 | ENSP00000372959 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.562 |
ESPNL | LRRC30 | ENSP00000339115 | ENSP00000372959 | Espin-like protein; Binds to but does not cross-link actin. Required for the formation and maintenance of inner ear hair cell stereocilia and staircase formation. Essential for normal hearing. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.596 |
LRRC14B | ASB10 | ENSP00000327675 | ENSP00000391137 | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.440 |
LRRC14B | ASB12 | ENSP00000327675 | ENSP00000355195 | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.585 |
LRRC14B | LRRC20 | ENSP00000327675 | ENSP00000348043 | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20. | 0.547 |
LRRC14B | LRRC30 | ENSP00000327675 | ENSP00000372959 | Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. | Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. | 0.609 |
LRRC20 | ASB10 | ENSP00000348043 | ENSP00000391137 | Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20. | Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.401 |