STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UROC1Urocanate hydratase 1. (736 aa)    
Predicted Functional Partners:
HAL
Histidine ammonia-lyase.
 
 
 0.995
AMDHD1
Probable imidazolonepropionase; Amidohydrolase domain containing 1.
  
 
 0.881
FTCD
Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool; In the N-terminal section; belongs to the formiminotransferase family.
  
  
 0.780
SLC22A10
Solute carrier family 22 member 10.
   
 
 0.529
GOLGA8M
Golgin A8 family member M.
      
 0.506
TXNRD3
Thioredoxin reductase 3; Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity).
      
 0.476
HGD
Homogentisate 1,2-dioxygenase.
   
  
 0.466
CSAG1
Putative chondrosarcoma-associated gene 1 protein; Chondrosarcoma associated gene 1.
      
 0.447
GRIP2
Glutamate receptor-interacting protein 2; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
   
 
 0.434
AGXT
Alanine--glyoxylate and serine--pyruvate aminotransferase.
   
 
 0.432
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.