STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM131AProtein FAM131A; Family with sequence similarity 131 member A. (366 aa)    
Predicted Functional Partners:
DPY19L4
Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
      
 0.540
ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C; Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
   
  
 0.494
VWA5B2
Von Willebrand factor A domain containing 5B2.
   
  
 0.486
OR10V1
Olfactory receptor 10V1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.479
DHRS13
Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase.
   
  
 0.479
C21orf62
Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.
      
 0.473
GFOD2
Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly.
   
    0.463
ABCF3
ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
   
  
 0.463
MAP6D1
MAP6 domain-containing protein 1; May have microtubule-stabilizing activity; Belongs to the STOP family.
   
  
 0.436
ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol.
   
  
 0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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