STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C6orf163Uncharacterized protein C6orf163; Chromosome 6 open reading frame 163. (329 aa)    
Predicted Functional Partners:
SMIM8
Small integral membrane protein 8.
 
 
  
 0.618
C1orf158
Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158.
   
  
 0.576
ZNF292
Zinc finger protein 292; May be involved in transcriptional regulation.
   
  
 0.534
CFAP206
Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
 
 
  
 0.529
WFDC10B
Protein WFDC10B; WAP four-disulfide core domain 10B.
      
 0.518
RWDD2A
RWD domain containing 2A.
      
 0.480
KRTAP4-9
Keratin associated protein 4-9.
      
 0.479
UBE3D
E3 ubiquitin-protein ligase E3D; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
   
  
 0.461
OR2H2
Olfactory receptor 2H2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.436
ZNF768
Zinc finger protein 768; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.434
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.