TMEM72 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7orf57	TMEM72	ENSP00000335500	ENSP00000374234	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Transmembrane protein 72.	0.445
HEATR6	SLC25A22	ENSP00000184956	ENSP00000322020	HEAT repeat-containing protein 6; Amplification-dependent oncogene.	Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+). Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.442
HEATR6	TMEM72	ENSP00000184956	ENSP00000374234	HEAT repeat-containing protein 6; Amplification-dependent oncogene.	Transmembrane protein 72.	0.478
LAMP5	TMEM72	ENSP00000246070	ENSP00000374234	Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.	Transmembrane protein 72.	0.433
MS4A1	TMEM72	ENSP00000433277	ENSP00000374234	B-lymphocyte antigen CD20; B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.	Transmembrane protein 72.	0.435
RIPOR3	TMEM72	ENSP00000045083	ENSP00000374234	RIPOR family member 3.	Transmembrane protein 72.	0.408
RNF181	TMEM72	ENSP00000306906	ENSP00000374234	E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Transmembrane protein 72.	0.461
SLC25A22	HEATR6	ENSP00000322020	ENSP00000184956	Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+). Belongs to the mitochondrial carrier (TC 2.A.29) family.	HEAT repeat-containing protein 6; Amplification-dependent oncogene.	0.442
SLC25A22	TMEM72	ENSP00000322020	ENSP00000374234	Mitochondrial glutamate carrier 1; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+). Belongs to the mitochondrial carrier (TC 2.A.29) family.	Transmembrane protein 72.	0.470
TMEM116	TMEM207	ENSP00000447731	ENSP00000346981	Transmembrane protein 116.	Transmembrane protein 207.	0.567
TMEM116	TMEM213	ENSP00000447731	ENSP00000390407	Transmembrane protein 116.	Transmembrane protein 213.	0.585
TMEM116	TMEM72	ENSP00000447731	ENSP00000374234	Transmembrane protein 116.	Transmembrane protein 72.	0.468
TMEM207	TMEM116	ENSP00000346981	ENSP00000447731	Transmembrane protein 207.	Transmembrane protein 116.	0.567
TMEM207	TMEM213	ENSP00000346981	ENSP00000390407	Transmembrane protein 207.	Transmembrane protein 213.	0.587
TMEM207	TMEM72	ENSP00000346981	ENSP00000374234	Transmembrane protein 207.	Transmembrane protein 72.	0.444
TMEM213	TMEM116	ENSP00000390407	ENSP00000447731	Transmembrane protein 213.	Transmembrane protein 116.	0.585
TMEM213	TMEM207	ENSP00000390407	ENSP00000346981	Transmembrane protein 213.	Transmembrane protein 207.	0.587
TMEM213	TMEM72	ENSP00000390407	ENSP00000374234	Transmembrane protein 213.	Transmembrane protein 72.	0.516
TMEM72	C7orf57	ENSP00000374234	ENSP00000335500	Transmembrane protein 72.	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	0.445
TMEM72	HEATR6	ENSP00000374234	ENSP00000184956	Transmembrane protein 72.	HEAT repeat-containing protein 6; Amplification-dependent oncogene.	0.478