STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM72Transmembrane protein 72. (275 aa)    
Predicted Functional Partners:
TMEM116
Transmembrane protein 116.
      
 0.623
RNF181
E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
      
 0.475
TMEM213
Transmembrane protein 213.
   
  
 0.459
C7orf57
Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.
      
 0.446
INSYN2B
Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family.
      
 0.434
TMEM207
Transmembrane protein 207.
   
  
 0.429
TMEM61
Transmembrane protein 61.
   
  
 0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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