node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMZ1 | CCDC57 | ENSP00000308149 | ENSP00000376154 | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | Coiled-coil domain containing 57. | 0.521 |
AMZ1 | FASTKD3 | ENSP00000308149 | ENSP00000264669 | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | 0.519 |
AMZ1 | NKAIN4 | ENSP00000308149 | ENSP00000359340 | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | 0.519 |
AMZ1 | RDM1 | ENSP00000308149 | ENSP00000483549 | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | RAD52 motif-containing protein 1; May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. | 0.476 |
BORCS6 | CCDC57 | ENSP00000373669 | ENSP00000376154 | BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS6 family. | Coiled-coil domain containing 57. | 0.479 |
CCDC57 | AMZ1 | ENSP00000376154 | ENSP00000308149 | Coiled-coil domain containing 57. | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | 0.521 |
CCDC57 | BORCS6 | ENSP00000376154 | ENSP00000373669 | Coiled-coil domain containing 57. | BLOC-1-related complex subunit 6; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS6 family. | 0.479 |
CCDC57 | FASN | ENSP00000376154 | ENSP00000304592 | Coiled-coil domain containing 57. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.642 |
CCDC57 | FASTKD3 | ENSP00000376154 | ENSP00000264669 | Coiled-coil domain containing 57. | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | 0.491 |
CCDC57 | NKAIN4 | ENSP00000376154 | ENSP00000359340 | Coiled-coil domain containing 57. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | 0.473 |
CCDC57 | PROSER3 | ENSP00000376154 | ENSP00000380116 | Coiled-coil domain containing 57. | Proline and serine rich 3. | 0.477 |
CCDC57 | RDM1 | ENSP00000376154 | ENSP00000483549 | Coiled-coil domain containing 57. | RAD52 motif-containing protein 1; May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. | 0.492 |
CCDC57 | SFI1 | ENSP00000376154 | ENSP00000383145 | Coiled-coil domain containing 57. | Protein SFI1 homolog; Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2. Belongs to the SFI1 family. | 0.509 |
CCDC57 | SLC16A11 | ENSP00000376154 | ENSP00000310490 | Coiled-coil domain containing 57. | Monocarboxylate transporter 11; Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane. Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids. | 0.543 |
CCDC57 | ZNF251 | ENSP00000376154 | ENSP00000292562 | Coiled-coil domain containing 57. | Zinc finger protein 251; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.528 |
FASN | CCDC57 | ENSP00000304592 | ENSP00000376154 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | Coiled-coil domain containing 57. | 0.642 |
FASTKD3 | AMZ1 | ENSP00000264669 | ENSP00000308149 | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. Belongs to the peptidase M54 family. | 0.519 |
FASTKD3 | CCDC57 | ENSP00000264669 | ENSP00000376154 | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | Coiled-coil domain containing 57. | 0.491 |
FASTKD3 | NKAIN4 | ENSP00000264669 | ENSP00000359340 | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Sodium/potassium transporting ATPase interacting 4; Belongs to the NKAIN family. | 0.476 |
FASTKD3 | RDM1 | ENSP00000264669 | ENSP00000483549 | FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. | RAD52 motif-containing protein 1; May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. | 0.458 |