STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM44Transmembrane protein 44. (475 aa)    
Predicted Functional Partners:
LSG1
Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).
   
  
 0.549
PPP1R18
Phostensin; [Isoform 1]: May target protein phosphatase 1 to F-actin cytoskeleton.
   
  
 0.518
FAM43A
Protein FAM43A; Family with sequence similarity 43 member A; Belongs to the FAM43 family.
   
  
 0.509
CALHM2
Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel.
   
  
 0.497
FAM86B1
Putative protein N-methyltransferase FAM86B1; Family with sequence similarity 86 member B1.
   
  
 0.484
ATP13A3
ATPase 13A3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
   
  
 0.480
ANO7
Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions. Belongs to the anoctamin family.
   
  
 0.466
C1orf226
Uncharacterized protein C1orf226; Chromosome 1 open reading frame 226.
      
 0.416
MCTP1
Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family.
      
 0.415
SNRNP48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein; Likely involved in U12-type 5' splice site recognition.
   
  
 0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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