node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14orf80 | C16orf59 | ENSP00000376307 | ENSP00000355022 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | 0.920 |
C14orf80 | C19orf25 | ENSP00000376307 | ENSP00000397394 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | 0.562 |
C14orf80 | CEP120 | ENSP00000376307 | ENSP00000303058 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Centrosomal protein of 120 kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis (By similarity); Belongs to the CEP120 family | 0.538 |
C14orf80 | CEP19 | ENSP00000376307 | ENSP00000387209 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes | 0.555 |
C14orf80 | CEP44 | ENSP00000376307 | ENSP00000389427 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Centrosomal protein of 44 kda; Centrosomal protein 44 | 0.640 |
C14orf80 | KIAA1731 | ENSP00000376307 | ENSP00000316681 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | 0.559 |
C14orf80 | RTTN | ENSP00000376307 | ENSP00000255674 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Rotatin; Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2; Armadillo-like helical domain containing | 0.527 |
C14orf80 | TMEM121 | ENSP00000376307 | ENSP00000376304 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Transmembrane protein 121; May play a role in MAPK signaling; Belongs to the TMEM121 family | 0.547 |
C14orf80 | TUBD1 | ENSP00000376307 | ENSP00000320797 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Tubulin delta chain; In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head; Tubulins | 0.570 |
C14orf80 | TUBE1 | ENSP00000376307 | ENSP00000357651 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | Tubulin epsilon chain; Belongs to the tubulin family | 0.863 |
C16orf59 | C14orf80 | ENSP00000355022 | ENSP00000376307 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | 0.920 |
C16orf59 | C19orf25 | ENSP00000355022 | ENSP00000397394 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | 0.519 |
C16orf59 | CEP120 | ENSP00000355022 | ENSP00000303058 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Centrosomal protein of 120 kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis (By similarity); Belongs to the CEP120 family | 0.523 |
C16orf59 | CEP19 | ENSP00000355022 | ENSP00000387209 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes | 0.540 |
C16orf59 | CEP44 | ENSP00000355022 | ENSP00000389427 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Centrosomal protein of 44 kda; Centrosomal protein 44 | 0.604 |
C16orf59 | KIAA1731 | ENSP00000355022 | ENSP00000316681 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | 0.545 |
C16orf59 | RTTN | ENSP00000355022 | ENSP00000255674 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Rotatin; Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2; Armadillo-like helical domain containing | 0.469 |
C16orf59 | TUBD1 | ENSP00000355022 | ENSP00000320797 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Tubulin delta chain; In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head; Tubulins | 0.664 |
C16orf59 | TUBE1 | ENSP00000355022 | ENSP00000357651 | Tubulin epsilon and delta complex 2; Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 | Tubulin epsilon chain; Belongs to the tubulin family | 0.852 |
C19orf25 | C14orf80 | ENSP00000397394 | ENSP00000376307 | UPF0449 protein C19orf25; Chromosome 19 open reading frame 25; Belongs to the UPF0449 family | Tubulin epsilon and delta complex 1; Uncharacterized protein C14orf80; Chromosome 14 open reading frame 80 | 0.562 |