GPR155 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF10L	GPR155	ENSP00000355060	ENSP00000376335	Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.	Integral membrane protein GPR155; G protein-coupled receptor 155.	0.442
ARHGEF10L	MORN5	ENSP00000355060	ENSP00000362869	Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.	MORN repeat containing 5.	0.497
ARHGEF10L	RIBC1	ENSP00000355060	ENSP00000364476	Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.	RIB43A domain with coiled-coils 1; Belongs to the RIB43A family.	0.485
ARHGEF10L	SCNM1	ENSP00000355060	ENSP00000357901	Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.	Sodium channel modifier 1; Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.	0.468
ATP11C	GPR155	ENSP00000332756	ENSP00000376335	Phospholipid-transporting ATPase IG; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. In the cell membrane of erythrocytes, it is required to maintain phosphatidylserine (PS) in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for [...]	Integral membrane protein GPR155; G protein-coupled receptor 155.	0.437
FPR2	GPR155	ENSP00000468897	ENSP00000376335	N-formyl peptide receptor 2; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti- inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effec [...]	Integral membrane protein GPR155; G protein-coupled receptor 155.	0.722
GPR137B	GPR155	ENSP00000355551	ENSP00000376335	Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.	Integral membrane protein GPR155; G protein-coupled receptor 155.	0.471
GPR137B	GPRC5C	ENSP00000355551	ENSP00000499092	Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.	G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways.	0.445
GPR155	ARHGEF10L	ENSP00000376335	ENSP00000355060	Integral membrane protein GPR155; G protein-coupled receptor 155.	Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.	0.442
GPR155	ATP11C	ENSP00000376335	ENSP00000332756	Integral membrane protein GPR155; G protein-coupled receptor 155.	Phospholipid-transporting ATPase IG; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. In the cell membrane of erythrocytes, it is required to maintain phosphatidylserine (PS) in the inner leaflet preventing its exposure on the surface. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized PS is a phagocytic signal for [...]	0.437
GPR155	FPR2	ENSP00000376335	ENSP00000468897	Integral membrane protein GPR155; G protein-coupled receptor 155.	N-formyl peptide receptor 2; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti- inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effec [...]	0.722
GPR155	GPR137B	ENSP00000376335	ENSP00000355551	Integral membrane protein GPR155; G protein-coupled receptor 155.	Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.	0.471
GPR155	GPRC5C	ENSP00000376335	ENSP00000499092	Integral membrane protein GPR155; G protein-coupled receptor 155.	G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways.	0.487
GPR155	JAKMIP1	ENSP00000376335	ENSP00000386711	Integral membrane protein GPR155; G protein-coupled receptor 155.	Janus kinase and microtubule-interacting protein 1; Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. Belongs to the JAKMIP family.	0.510
GPR155	MORN5	ENSP00000376335	ENSP00000362869	Integral membrane protein GPR155; G protein-coupled receptor 155.	MORN repeat containing 5.	0.477
GPR155	RIBC1	ENSP00000376335	ENSP00000364476	Integral membrane protein GPR155; G protein-coupled receptor 155.	RIB43A domain with coiled-coils 1; Belongs to the RIB43A family.	0.473
GPR155	SCNM1	ENSP00000376335	ENSP00000357901	Integral membrane protein GPR155; G protein-coupled receptor 155.	Sodium channel modifier 1; Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.	0.466
GPR155	SOGA1	ENSP00000376335	ENSP00000237536	Integral membrane protein GPR155; G protein-coupled receptor 155.	C-terminal 80 kDa form; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. Belongs to the SOGA family.	0.484
GPRC5C	GPR137B	ENSP00000499092	ENSP00000355551	G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways.	Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.	0.445
GPRC5C	GPR155	ENSP00000499092	ENSP00000376335	G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways.	Integral membrane protein GPR155; G protein-coupled receptor 155.	0.487