BCL2L15 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP4B1	BCL2L15	ENSP00000358582	ENSP00000376992	AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asy [...]	Bcl-2-like protein 15; BCL2 like 15.	0.524
AP4B1	PHTF1	ENSP00000358582	ENSP00000358617	AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asy [...]	Putative homeodomain transcription factor 1; May play a role in transcription regulation.	0.549
AP4B1	RSBN1	ENSP00000358582	ENSP00000261441	AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asy [...]	Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture.	0.579
BCL2L10	BCL2L14	ENSP00000453562	ENSP00000309132	Bcl-2-like protein 10; Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	0.504
BCL2L10	BCL2L15	ENSP00000453562	ENSP00000376992	Bcl-2-like protein 10; Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.	Bcl-2-like protein 15; BCL2 like 15.	0.465
BCL2L12	BCL2L13	ENSP00000482218	ENSP00000480836	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	0.699
BCL2L12	BCL2L14	ENSP00000482218	ENSP00000309132	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	0.485
BCL2L12	BCL2L15	ENSP00000482218	ENSP00000376992	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	Bcl-2-like protein 15; BCL2 like 15.	0.446
BCL2L13	BCL2L12	ENSP00000480836	ENSP00000482218	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	0.699
BCL2L13	BCL2L14	ENSP00000480836	ENSP00000309132	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	0.834
BCL2L13	BCL2L15	ENSP00000480836	ENSP00000376992	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	Bcl-2-like protein 15; BCL2 like 15.	0.474
BCL2L14	BCL2L10	ENSP00000309132	ENSP00000453562	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	Bcl-2-like protein 10; Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.	0.504
BCL2L14	BCL2L12	ENSP00000309132	ENSP00000482218	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	0.485
BCL2L14	BCL2L13	ENSP00000309132	ENSP00000480836	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	0.834
BCL2L14	BCL2L15	ENSP00000309132	ENSP00000376992	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	Bcl-2-like protein 15; BCL2 like 15.	0.673
BCL2L15	AP4B1	ENSP00000376992	ENSP00000358582	Bcl-2-like protein 15; BCL2 like 15.	AP-4 complex subunit beta-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asy [...]	0.524
BCL2L15	BCL2L10	ENSP00000376992	ENSP00000453562	Bcl-2-like protein 15; BCL2 like 15.	Bcl-2-like protein 10; Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.	0.465
BCL2L15	BCL2L12	ENSP00000376992	ENSP00000482218	Bcl-2-like protein 15; BCL2 like 15.	Bcl-2-like protein 12; BCL2 like 12; Belongs to the Bcl-2 family.	0.446
BCL2L15	BCL2L13	ENSP00000376992	ENSP00000480836	Bcl-2-like protein 15; BCL2 like 15.	Bcl-2-like protein 13; May promote the activation of caspase-3 and apoptosis.	0.474
BCL2L15	BCL2L14	ENSP00000376992	ENSP00000309132	Bcl-2-like protein 15; BCL2 like 15.	Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis.	0.673