node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC2 | CFAP44 | ENSP00000376417 | ENSP00000377428 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.665 |
ARMC2 | CFAP69 | ENSP00000376417 | ENSP00000373948 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability. | 0.679 |
ARMC2 | CFAP70 | ENSP00000376417 | ENSP00000310829 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Cilia and flagella associated protein 70; Belongs to the CFAP70 family. | 0.704 |
ARMC2 | DNAH1 | ENSP00000376417 | ENSP00000401514 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | 0.649 |
ARMC2 | FSIP2 | ENSP00000376417 | ENSP00000401306 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis. | 0.607 |
ARMC2 | QRICH2 | ENSP00000376417 | ENSP00000262765 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility. | 0.699 |
ARMC2 | SPEF2 | ENSP00000376417 | ENSP00000348314 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation. | 0.717 |
ARMC2 | TTC21A | ENSP00000376417 | ENSP00000398211 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs to the TTC21 family. | 0.689 |
ARMC2 | TTC29 | ENSP00000376417 | ENSP00000423505 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | Tetratricopeptide repeat domain 29. | 0.659 |
ARMC2 | WDR19 | ENSP00000376417 | ENSP00000382717 | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | WD repeat-containing protein 19; As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport (By similarity). | 0.460 |
CFAP44 | ARMC2 | ENSP00000377428 | ENSP00000376417 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Armadillo repeat-containing protein 2; Required for sperm flagellum axoneme organization and function (By similarity). Involved in axonemal central pair complex assembly and/or stability (By similarity). | 0.665 |
CFAP44 | CFAP69 | ENSP00000377428 | ENSP00000373948 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability. | 0.800 |
CFAP44 | CFAP70 | ENSP00000377428 | ENSP00000310829 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Cilia and flagella associated protein 70; Belongs to the CFAP70 family. | 0.722 |
CFAP44 | DNAH1 | ENSP00000377428 | ENSP00000401514 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme ; Belongs to the dynein heavy chain family. | 0.784 |
CFAP44 | FSIP2 | ENSP00000377428 | ENSP00000401306 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis. | 0.664 |
CFAP44 | QRICH2 | ENSP00000377428 | ENSP00000262765 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility. | 0.808 |
CFAP44 | SPEF2 | ENSP00000377428 | ENSP00000348314 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation. | 0.676 |
CFAP44 | TTC21A | ENSP00000377428 | ENSP00000398211 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs to the TTC21 family. | 0.693 |
CFAP44 | TTC29 | ENSP00000377428 | ENSP00000423505 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | Tetratricopeptide repeat domain 29. | 0.665 |
CFAP44 | WDR19 | ENSP00000377428 | ENSP00000382717 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function. | WD repeat-containing protein 19; As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein- coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport (By similarity). | 0.672 |