METTL7B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

METTL7B

Methyltransferase-like protein 7B; Probable methyltransferase. (244 aa)

Predicted Functional Partners:

METTL25

0.627

RTN4

0.620

EEF1AKMT2

0.615

METTL8

0.604

PUM2

0.510

GRPR

0.510

PUM1

0.510

METTL2B

0.500

PLEKHA4

0.496

CDC123

0.460

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC123	METTL7B	ENSP00000281141	ENSP00000377796	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Methyltransferase-like protein 7B; Probable methyltransferase.	0.460
EEF1AKMT2	METTL25	ENSP00000357829	ENSP00000248306	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Methyltransferase-like protein 25; Putative methyltransferase.	0.656
EEF1AKMT2	METTL2B	ENSP00000357829	ENSP00000262432	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	0.551
EEF1AKMT2	METTL7B	ENSP00000357829	ENSP00000377796	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	Methyltransferase-like protein 7B; Probable methyltransferase.	0.615
EEF1AKMT2	METTL8	ENSP00000357829	ENSP00000480056	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs.	0.569
GRPR	METTL7B	ENSP00000369643	ENSP00000377796	Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By si [...]	Methyltransferase-like protein 7B; Probable methyltransferase.	0.510
METTL25	EEF1AKMT2	ENSP00000248306	ENSP00000357829	Methyltransferase-like protein 25; Putative methyltransferase.	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	0.656
METTL25	METTL2B	ENSP00000248306	ENSP00000262432	Methyltransferase-like protein 25; Putative methyltransferase.	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	0.619
METTL25	METTL7B	ENSP00000248306	ENSP00000377796	Methyltransferase-like protein 25; Putative methyltransferase.	Methyltransferase-like protein 7B; Probable methyltransferase.	0.627
METTL25	METTL8	ENSP00000248306	ENSP00000480056	Methyltransferase-like protein 25; Putative methyltransferase.	mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs.	0.657
METTL2B	EEF1AKMT2	ENSP00000262432	ENSP00000357829	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	0.551
METTL2B	METTL25	ENSP00000262432	ENSP00000248306	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	Methyltransferase-like protein 25; Putative methyltransferase.	0.619
METTL2B	METTL7B	ENSP00000262432	ENSP00000377796	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	Methyltransferase-like protein 7B; Probable methyltransferase.	0.500
METTL2B	PLEKHA4	ENSP00000262432	ENSP00000263265	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.	0.457
METTL7B	CDC123	ENSP00000377796	ENSP00000281141	Methyltransferase-like protein 7B; Probable methyltransferase.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	0.460
METTL7B	EEF1AKMT2	ENSP00000377796	ENSP00000357829	Methyltransferase-like protein 7B; Probable methyltransferase.	EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.	0.615
METTL7B	GRPR	ENSP00000377796	ENSP00000369643	Methyltransferase-like protein 7B; Probable methyltransferase.	Gastrin-releasing peptide receptor; Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By si [...]	0.510
METTL7B	METTL25	ENSP00000377796	ENSP00000248306	Methyltransferase-like protein 7B; Probable methyltransferase.	Methyltransferase-like protein 25; Putative methyltransferase.	0.627
METTL7B	METTL2B	ENSP00000377796	ENSP00000262432	Methyltransferase-like protein 7B; Probable methyltransferase.	tRNA N(3)-methylcytidine methyltransferase METTL2B; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU). Belongs to the methyltransferase superfamily. METL family.	0.500
METTL7B	METTL8	ENSP00000377796	ENSP00000480056	Methyltransferase-like protein 7B; Probable methyltransferase.	mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs.	0.604