Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP5S1 | ARFGAP2 | ENSP00000481750 | ENSP00000434442 | AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to it is required for efficient homologous recombination DNA double-strand break repair. | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. | 0.470 |
| AP5S1 | ZBTB3 | ENSP00000481750 | ENSP00000501025 | AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to it is required for efficient homologous recombination DNA double-strand break repair. | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.512 |
| AP5S1 | ZNF367 | ENSP00000481750 | ENSP00000364405 | AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to it is required for efficient homologous recombination DNA double-strand break repair. | Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes. | 0.460 |
| ARFGAP2 | AP5S1 | ENSP00000434442 | ENSP00000481750 | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. | AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to it is required for efficient homologous recombination DNA double-strand break repair. | 0.470 |
| ARFGAP2 | ZBTB3 | ENSP00000434442 | ENSP00000501025 | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.419 |
| ARFGAP2 | ZNF367 | ENSP00000434442 | ENSP00000364405 | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. | Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes. | 0.427 |
| NR2C2AP | ZBTB3 | ENSP00000402756 | ENSP00000501025 | Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes; Belongs to the NR2C2AP family. | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.428 |
| SPOP | ZBTB3 | ENSP00000377001 | ENSP00000501025 | Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING- [...] | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.499 |
| SRCAP | ZBTB3 | ENSP00000262518 | ENSP00000501025 | Helicase SRCAP; Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch- mediated transcription. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.429 |
| ZBTB18 | ZBTB3 | ENSP00000351539 | ENSP00000501025 | Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May [...] | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | 0.591 |
| ZBTB3 | AP5S1 | ENSP00000501025 | ENSP00000481750 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | AP-5 complex subunit sigma-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to it is required for efficient homologous recombination DNA double-strand break repair. | 0.512 |
| ZBTB3 | ARFGAP2 | ENSP00000501025 | ENSP00000434442 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. | 0.419 |
| ZBTB3 | NR2C2AP | ENSP00000501025 | ENSP00000402756 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes; Belongs to the NR2C2AP family. | 0.428 |
| ZBTB3 | SPOP | ENSP00000501025 | ENSP00000377001 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING- [...] | 0.499 |
| ZBTB3 | SRCAP | ENSP00000501025 | ENSP00000262518 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Helicase SRCAP; Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch- mediated transcription. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. | 0.429 |
| ZBTB3 | ZBTB18 | ENSP00000501025 | ENSP00000351539 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May [...] | 0.591 |
| ZBTB3 | ZNF367 | ENSP00000501025 | ENSP00000364405 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes. | 0.444 |
| ZBTB3 | ZNF554 | ENSP00000501025 | ENSP00000321132 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Zinc finger protein 554; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.422 |
| ZBTB3 | ZNF646 | ENSP00000501025 | ENSP00000300850 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Zinc finger protein 646; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.431 |
| ZBTB3 | ZNF8 | ENSP00000501025 | ENSP00000477716 | Zinc finger and BTB domain-containing protein 3; May be involved in transcriptional regulation. | Zinc finger protein 8; Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins. Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.445 |
page 1 of 2