node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C7orf26 | FBXO42 | ENSP00000340220 | ENSP00000364742 | Uncharacterized protein C7orf26; Chromosome 7 open reading frame 26. | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. | 0.499 |
C7orf26 | HERPUD2 | ENSP00000340220 | ENSP00000379390 | Uncharacterized protein C7orf26; Chromosome 7 open reading frame 26. | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.516 |
FAM8A1 | HERPUD2 | ENSP00000259963 | ENSP00000379390 | Protein FAM8A1; Family with sequence similarity 8 member A1. | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.504 |
FAM8A1 | TMUB1 | ENSP00000259963 | ENSP00000376565 | Protein FAM8A1; Family with sequence similarity 8 member A1. | Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity). | 0.574 |
FAM8A1 | TMUB2 | ENSP00000259963 | ENSP00000444565 | Protein FAM8A1; Family with sequence similarity 8 member A1. | Transmembrane and ubiquitin like domain containing 2. | 0.507 |
FBXO42 | C7orf26 | ENSP00000364742 | ENSP00000340220 | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. | Uncharacterized protein C7orf26; Chromosome 7 open reading frame 26. | 0.499 |
FBXO42 | HERPUD2 | ENSP00000364742 | ENSP00000379390 | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.406 |
HERPUD2 | C7orf26 | ENSP00000379390 | ENSP00000340220 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Uncharacterized protein C7orf26; Chromosome 7 open reading frame 26. | 0.516 |
HERPUD2 | FAM8A1 | ENSP00000379390 | ENSP00000259963 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Protein FAM8A1; Family with sequence similarity 8 member A1. | 0.504 |
HERPUD2 | FBXO42 | ENSP00000379390 | ENSP00000364742 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. | 0.406 |
HERPUD2 | OGFOD1 | ENSP00000379390 | ENSP00000457258 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family. | 0.474 |
HERPUD2 | OR4F6 | ENSP00000379390 | ENSP00000327525 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Olfactory receptor 4F6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.433 |
HERPUD2 | TMUB1 | ENSP00000379390 | ENSP00000376565 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity). | 0.406 |
HERPUD2 | TMUB2 | ENSP00000379390 | ENSP00000444565 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | Transmembrane and ubiquitin like domain containing 2. | 0.493 |
OGFOD1 | HERPUD2 | ENSP00000457258 | ENSP00000379390 | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family. | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.474 |
OR4F6 | HERPUD2 | ENSP00000327525 | ENSP00000379390 | Olfactory receptor 4F6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.433 |
TMUB1 | FAM8A1 | ENSP00000376565 | ENSP00000259963 | Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity). | Protein FAM8A1; Family with sequence similarity 8 member A1. | 0.574 |
TMUB1 | HERPUD2 | ENSP00000376565 | ENSP00000379390 | Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity). | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway. | 0.406 |
TMUB1 | TMUB2 | ENSP00000376565 | ENSP00000444565 | Transmembrane and ubiquitin-like domain-containing protein 1; Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity). | Transmembrane and ubiquitin like domain containing 2. | 0.844 |
TMUB2 | FAM8A1 | ENSP00000444565 | ENSP00000259963 | Transmembrane and ubiquitin like domain containing 2. | Protein FAM8A1; Family with sequence similarity 8 member A1. | 0.507 |