STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIGD7Tigger transposable element derived 7; Belongs to the tigger transposable element derived protein family. (549 aa)    
Predicted Functional Partners:
ZNF75A
Zinc finger protein 75A; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.621
CENPBD1
CENPB DNA-binding domain containing 1.
  
  
 0.605
POGK
Pogo transposable element derived with KRAB domain.
      
 0.569
ZNF200
Zinc finger protein 200; Could have a role in spermatogenesis.
   
  
 0.528
NAIF1
Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.
   
  
 0.492
ZNF681
Zinc finger protein 681; May be involved in transcriptional regulation.
   
  
 0.485
OR52N4
Olfactory receptor 52N4; Odorant receptor.
      
 0.480
UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats; Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
   
   0.478
ZNF263
Zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.466
TIGD1
Tigger transposable element derived 1.
  
  
0.459
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.